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ARHGEF7 产品

(rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

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Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Featured ARHGEF7 Categories

ARHGEF7 抗体

High quality antibodies with extensive validation data.

ARHGEF7 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ARHGEF7 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ARHGEF7 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7240553
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IP, IF
Validations
  • (2)
Cat. No. ABIN7167994
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, ICC
Validations
  • (1)
  • (1)
Cat. No. ABIN1169227
Quantity 100 μg
Datasheet Datasheet

Recommended ARHGEF7 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959165
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674757
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674758
Quantity 96 tests
Datasheet Datasheet

Recommended ARHGEF7 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124865
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345566
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7399892
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ARHGEF7 Products

Valdes, Tang, McDermott, Kuo, Zimmerman, Wincovitch, Waterman, Milgram, Playford et al.: "Sorting nexin 27 protein regulates trafficking of a p21-activated kinase (PAK) interacting exchange factor (β-Pix)-G protein-coupled receptor kinase interacting protein (GIT) complex via a PDZ domain ..." in: The Journal of biological chemistry, Vol. 286, Issue 45, pp. 39403-16, (2011) (PubMed).

Turner, Brown, Perrotta, Riedy, Nikolopoulos, McDonald, Bagrodia, Thomas, Leventhal: "Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling." in: The Journal of cell biology, Vol. 145, Issue 4, pp. 851-63, (1999) (PubMed).

Bagrodia, Taylor, Jordon, Van Aelst, Cerione: "A novel regulator of p21-activated kinases." in: The Journal of biological chemistry, Vol. 273, Issue 37, pp. 23633-6, (1998) (PubMed).

Manser, Loo, Koh, Zhao, Chen, Tan, Tan, Leung, Lim: "PAK kinases are directly coupled to the PIX family of nucleotide exchange factors." in: Molecular cell, Vol. 1, Issue 2, pp. 183-92, (1998) (PubMed).

Oh, Yoo, Jo, Song, Kim, Park: "Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).

Synonyms and alternative names related to ARHGEF7

Rho guanine nucleotide exchange factor 7 (ARHGEF7), Rho guanine nucleotide exchange factor 7 S homeolog (arhgef7.S), Rho guanine nucleotide exchange factor 7 (arhgef7), ankyrin repeat domain 10 (ANKRD10), Rho guanine nucleotide exchange factor 7 (Arhgef7), Rho guanine nucleotide exchange factor (GEF7) (Arhgef7), Rho guanine nucleotide exchange factor (GEF) 7b (arhgef7b), ARHGEF7, arhgef7, bbh, BETA-PIX, betaPix, betaPix-b, betaPix-c, bpix, Cool, COOL-1, cool-1, COOL1, cool1, im:7142367, mKIAA0142, Nbla10314, P50, p50, P50BP, P85, p85, P85COOL1, p85Cool1, P85SPR, P85spr, p85SPR, PAK3, pak3, Pak3bp, PIX, PIXB, pixb, wu:fc35h08, zgc:101775

Protein level used designations for ARHGEF7

  • PAK-interacting exchange factor beta
  • SH3 domain-containing proline-rich protein
  • guanine nucleotide exchange factor 7
  • rho guanine nucleotide exchange factor 7
  • Rho guanine nucleotide exchange factor (GEF) 7
  • Rho guanine nucleotide exchange factor 7
  • rho guanine nucleotide exchange factor 7-like
  • beta-Pix
  • Pak interacting exchange factor
  • Pak3 binding protein
  • Rho guanine exchange factor betaPix
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