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ARHGEF11 产品

(rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

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Featured ARHGEF11 Categories

ARHGEF11 抗体

High quality antibodies with extensive validation data.

ARHGEF11 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ARHGEF11 抗体

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Reactivity
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Cat. No.
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Datasheet
Reactivity Human
Application WB, ELISA
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Cat. No. ABIN523257
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p)
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Cat. No. ABIN961419
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
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  • (1)
Cat. No. ABIN7184414
Quantity 100 μL
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Recommended ARHGEF11 蛋白

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Source Wheat germ
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Cat. No. ABIN1345537
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
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Cat. No. ABIN2714890
Quantity 20 μg
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Latest Publications for our ARHGEF11 Products

Ding, Dhruv, Kwiatkowska-Piwowarczyk, Ruggieri, Kloss, Symons, Pirrotte, Eschbacher, Tran, Loftus: "PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival." in: Neoplasia (New York, N.Y.), Vol. 20, Issue 10, pp. 1045-1058, (2019) (PubMed).

Rozbicki, Chuai, Karjalainen, Song, Sang, Martin, Knölker, MacDonald, Weijer: "Myosin-II-mediated cell shape changes and cell intercalation contribute to primitive streak formation." in: Nature cell biology, Vol. 17, Issue 4, pp. 397-408, (2015) (PubMed).

Jia, Johnson, Wang, Guo, Dreisbach, Lewin, Kyle, Garrett: "Allelic Variants in Arhgef11 via the Rho-Rock Pathway Are Linked to Epithelial-Mesenchymal Transition and Contributes to Kidney Injury in the Dahl Salt-Sensitive Rat." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132553, (2015) (PubMed).

Härmä, Knuuttila, Virtanen, Mirtti, Kohonen, Kovanen, Happonen, Kaewphan, Ahonen, Kallioniemi, Grafström, Lötjönen, Nees: "Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models." in: Oncogene, Vol. 31, Issue 16, pp. 2075-89, (2012) (PubMed).

Synonyms and alternative names related to ARHGEF11

Rho guanine nucleotide exchange factor (GEF) 11 (arhgef11), Rho guanine nucleotide exchange factor 11 (ARHGEF11), Rho guanine nucleotide exchange factor (GEF) 11 (Arhgef11), Rho guanine nucleotide exchange factor 11 (Arhgef11), rho guanine nucleotide exchange factor 11 (LOC511220), ARHGEF11, B930073M02, E130307F09, GTRAP48, Gtrap48, mKIAA0380, PDZ-RHOGEF, PDZ-RhoGEF, Prg, RhoGEF

Protein level used designations for ARHGEF11

  • PDZ-RhoGEF
  • rho guanine nucleotide exchange factor 11
  • Rho guanine nucleotide exchange factor (GEF) 11
  • rho guanine nucleotide exchange factor 11-like
  • Rho guanine exchange factor (GEF) 11
  • RhoA-specific guanine nucleotide exchange factor
  • RhoGEF glutamate transport modulator
  • glutamate transporter EAAT4-associated protein 48
  • RhoGEF glutamate transport modulator GTRAP48
  • glutamate transporter EAAT4 associated protein 48
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