ARFGEF2 抗体
(ADP-Ribosylation Factor Guanine Nucleotide-Exchange Factor 2 (Brefeldin A-Inhibited) (ARFGEF2))
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008].
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ARFGEF2 抗体
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Latest Publications for our ARFGEF2 Products
: "Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 34, pp. E3162-70, (2013) (PubMed).: "The small G protein Arl1 directs the trans-Golgi-specific targeting of the Arf1 exchange factors BIG1 and BIG2." in: The Journal of cell biology, Vol. 196, Issue 3, pp. 327-35, (2012) (PubMed).
: "cAMP-dependent protein kinase A (PKA) signaling induces TNFR1 exosome-like vesicle release via anchoring of PKA regulatory subunit RIIbeta to BIG2." in: The Journal of biological chemistry, Vol. 283, Issue 37, pp. 25364-71, (2008) (PubMed).
Synonyms and alternative names related to ARFGEF2
ADP ribosylation factor guanine nucleotide exchange factor 2 (ARFGEF2), ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) (Arfgef2), ADP ribosylation factor guanine nucleotide exchange factor 2 (Arfgef2), AI463430, AW493672, BIG2, Big2, dJ1164I10.1, E230011G24Rik, PVNH2Protein level used designations for ARFGEF2
- ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- cytohesin 1-like
- brefeldin A-inhibited GEP 2
- brefeldin A-inhibited guanine nucleotide-exchange protein 2
- Brefeldin A-inhibited guanine nucleotide-exchange factor 2
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