ARAP1 产品
(ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))
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The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
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Featured ARAP1 Categories
Recommended ARAP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IP, ICC
Validations
- (1)
- (2)
Cat. No.
ABIN302078
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7144564
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC, WB
Validations
- (2)
Cat. No.
ABIN185099
Quantity
100 μg
Datasheet
Datasheet
Recommended ARAP1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345438
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345440
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3089102
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ARAP1 Products
: "ARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf5." in: Molecular biology of the cell, Vol. 23, Issue 13, pp. 2481-9, (2012) (PubMed).: "Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane." in: Apoptosis : an international journal on programmed cell death, Vol. 13, Issue 3, pp. 423-36, (2008) (PubMed).
: "Comparison of effects of PKA catalytic subunit on I(h) and calcium channel currents in rat dorsal root ganglion cells." in: Biomedical research (Tokyo, Japan), Vol. 28, Issue 4, pp. 177-89, (2007) (PubMed).
: "ARAP1: a point of convergence for Arf and Rho signaling." in: Molecular cell, Vol. 9, Issue 1, pp. 109-19, (2002) (PubMed).
: "cAMP-independent role of PKA in tonicity-induced transactivation of tonicity-responsive enhancer/ osmotic response element-binding protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16800-5, (2002) (PubMed).
Synonyms and alternative names related to ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 (ARAP1), centaurin, delta 2 (centd2), ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 (Arap1), 2410002L19Rik, ARAP1, CENTD2, Centd2, Ci-ArfGAP-8, mKIAA0782Protein level used designations for ARAP1
- centaurin delta 2
- centaurin, delta 2
- ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
- arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
- centaurin-delta-2
- cnt-d2
- ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1
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