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APPL2 蛋白

(Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 2 (APPL2))

The protein encoded by this gene is one of two effectors of the small GTPase RAB5A/Rab5, which are involved in a signal transduction pathway. Both effectors contain an N-terminal Bin/Amphiphysin/Rvs (BAR) domain, a central pleckstrin homology (PH) domain, and a C-terminal phosphotyrosine binding (PTB) domain, and they bind the Rab5 through the BAR domain. They are associated with endosomal membranes and can be translocated to the nucleus in response to the EGF stimulus. They interact with the NuRD/MeCP1 complex (nucleosome remodeling and deacetylase /methyl-CpG-binding protein 1 complex) and are required for efficient cell proliferation. A chromosomal aberration t(12\;22)(q24.1\;q13.3) involving this gene and the PSAP2 gene results in 22q13.3 deletion syndrome, also known as Phelan-McDermid syndrome. [provided by RefSeq, Oct 2011].

recommended

APPL2 Protein (AA 403-664) (His tag) (ABIN7121696)

APPL2 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB

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recommended

APPL2 Protein (AA 174-273) (GST tag) (ABIN1345412)

APPL2 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

APPL2 Protein (AA 1-664) (GST tag) (ABIN1345410)

APPL2 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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APPL2 蛋白 by Origin

Find APPL2 蛋白 for a variety of species such as anti-Human APPL2, anti-Mouse APPL2. The species listed below are among those available. Click on a link to go to the corresponding products.

APPL2 蛋白 by Source

Here you will find APPL2 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

APPL2 蛋白 by 蛋白类型

Here you can find APPL2 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

APPL2 蛋白 by 应用范围

Find APPL2 蛋白 validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular APPL2 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

APPL2 Protein (AA 403-664) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7121696

Quantity 50 μg

Datasheet Datasheet

APPL2 Protein (AA 174-273) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1345412

Quantity 10 μg

Datasheet Datasheet

APPL2 Protein (AA 1-664) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1345410

Quantity 10 μg

Datasheet Datasheet

APPL2 Protein (AA 1-664) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3078974

Quantity 1 mg

Datasheet Datasheet

APPL2 Protein (AA 1-662) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3126402

Quantity 1 mg

Datasheet Datasheet

APPL2 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2714848

Quantity 20 μg

Datasheet Datasheet

Aliases for APPL2 蛋白

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (Appl2) 蛋白
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (APPL2) 蛋白
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 L homeolog (appl2.L) 蛋白
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (appl2) 蛋白
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 (appl2) 蛋白
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 (Appl2) 蛋白
APPL2 蛋白
Dip3b 蛋白
dip13b 蛋白
DIP13B 蛋白
MGC84621 蛋白
RGD1563028 蛋白

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APPL2 蛋白 by Origin

APPL2 蛋白 by Source

APPL2 蛋白 by 蛋白类型

APPL2 蛋白 by 应用范围

Popular APPL2 蛋白

Aliases for APPL2 蛋白

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