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APP 蛋白

(Amyloid beta (A4) Precursor Protein (APP))
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
APP Protein (AA 19-305) (GST tag) APP Protein (AA 19-305) (GST tag) APP Protein (AA 19-305) (GST tag) (ABIN1345399)

APP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

APP Protein (AA 1-305) (GST tag) APP Protein (AA 1-305) (GST tag) APP Protein (AA 1-305) (GST tag) (ABIN1345401)

APP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

APP Protein (AA 18-669) (His tag) APP Protein (AA 18-669) (His tag) APP Protein (AA 18-669) (His tag) (ABIN7092740)

APP 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.

APP 蛋白 by Grade

Find APP 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

APP 蛋白 by Origin

Find APP 蛋白 for a variety of species such as anti-Human APP, anti-Mouse APP, anti-Rat APP. The species listed below are among those available. Click on a link to go to the corresponding products.

APP 蛋白 by Source

Here you will find APP 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

APP 蛋白 by 蛋白类型

Here you can find APP 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

APP 蛋白 by 应用范围

Find APP 蛋白 validated for a specific application such as WB, SDS, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

APP 蛋白 by 生物活性

Find APP 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular APP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345399
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345401
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7092740
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2714676
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7392971
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423663
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423672
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7392974
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7402439
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7400156
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7536320
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7194239
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2127988
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3008253
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2714677
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our APP 蛋白

Planque, Nishiyama, Sonoda, Lin, Taguchi, Hara, Kolodziej, Mitsuda, Gonzalez, Sait, Fukuchi, Massey, Friedland, ONuallain, Sigurdsson, Paul: "Specific amyloid β clearance by a catalytic antibody construct." in: The Journal of biological chemistry, Vol. 290, Issue 16, pp. 10229-41, (2015) (PubMed).

Yoshikai, Sasaki, Doh-ura, Furuya, Sakaki: "Genomic organization of the human amyloid beta-protein precursor gene." in: Gene, Vol. 87, Issue 2, pp. 257-63, (1990) (PubMed).

Lemaire, Salbaum, Multhaup, Kang, Bayney, Unterbeck, Beyreuther, Müller-Hill: "The PreA4(695) precursor protein of Alzheimer's disease A4 amyloid is encoded by 16 exons." in: Nucleic acids research, Vol. 17, Issue 2, pp. 517-22, (1989) (PubMed).

Ponte, Gonzalez-DeWhitt, Schilling, Miller, Hsu, Greenberg, Davis, Wallace, Lieberburg, Fuller: "A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors." in: Nature, Vol. 331, Issue 6156, pp. 525-7, (1988) (PubMed).

Kang, Lemaire, Unterbeck, Salbaum, Masters, Grzeschik, Multhaup, Beyreuther, Müller-Hill: "The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor." in: Nature, Vol. 325, Issue 6106, pp. 733-6, (1987) (PubMed).

Aliases for APP 蛋白

amyloid beta precursor protein (APP) 蛋白
amyloid beta (A4) precursor protein (APP) 蛋白
amyloid beta precursor protein (app) 蛋白
beta amyloid protein precursor-like (Appl) 蛋白
amyloid beta precursor protein (App) 蛋白
amyloid beta (A4) precursor protein (App) 蛋白
amyloid beta (A4) precursor protein a (appa) 蛋白
amyloid beta precursor protein L homeolog (app.L) 蛋白
AAA 蛋白
aaa 蛋白
ABETA 蛋白
abeta 蛋白
Abeta 蛋白
ABPP 蛋白
abpp 蛋白
Abpp 蛋白
AD1 蛋白
ad1 蛋白
Adap 蛋白
Ag 蛋白
APP 蛋白
app 蛋白
APP-like 蛋白
APPI 蛋白
appi 蛋白
APPL 蛋白
appl 蛋白
BcDNA:GH04413 蛋白
betaApp 蛋白
CG7727 蛋白
CTFgamma 蛋白
ctfgamma 蛋白
CVAP 蛋白
cvap 蛋白
Cvap 蛋白
Dmel\\CG7727 蛋白
E030013M08Rik 蛋白
EG:65F1.5 蛋白
PN-II 蛋白
PN2 蛋白
pn2 蛋白
wu:fj34d10 蛋白
wu:fk65e12 蛋白
zgc:85740 蛋白
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