Apoptosis Protease Activating Factor 1 ELISA试剂盒
(Apoptosis Protease Activating Factor 1)
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Latest Publications for our Apoptosis Protease Activating Factor 1 Products
: "The role of miR-19b in the inhibition of endothelial cell apoptosis and its relationship with coronary artery disease." in: Scientific reports, Vol. 5, pp. 15132, (2016) (PubMed).Synonyms and alternative names related to Apoptosis Protease Activating Factor 1
apoptotic peptidase activating factor 1 (APAF1), APAF-1, CED4Protein level used designations for Apoptosis Protease Activating Factor 1
- apoptotic protease-activating factor 1
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