APOBEC3A/B 抗体 (Internal Region)
This 兔 多克隆 antibody specifically detects APOBEC3A/B in IHC 和 WB. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN6259985
发货至:
中国
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北京 101111
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Quick Overview for APOBEC3A/B 抗体 (Internal Region) (ABIN6259985)
抗原
See all APOBEC3A/B (APOBEC3A_B) products
APOBEC3A/B (APOBEC3A_B)
(APOBEC3A and APOBEC3B Deletion Hybrid (APOBEC3A_B))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
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抗原表位
- Internal Region
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原理
- APOBEC3A/B Antibody
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特异性
- APOBEC3A/B Antibody detects endogenous levels of total APOBEC3A/B
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预测反应
- Rabbit
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human APOBEC3A/B, corresponding to a region within the internal amino acids.
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亚型
- IgG
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应用备注
- WB 1:1000-3000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- APOBEC3A/B (APOBEC3A_B) (APOBEC3A and APOBEC3B Deletion Hybrid (APOBEC3A_B))
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别名
- APOBEC3A/B
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背景
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Description: DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Gene: APOBEC3A
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分子量
- 23 kDa,46 kDa
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基因ID
- 100, 913, 187
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UniProt
- P31941
抗原
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