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APOA5 产品

(Apolipoprotein A-V (APOA5))

Categories

The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009].

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Featured APOA5 Categories

APOA5 抗体

High quality antibodies with extensive validation data.

APOA5 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

APOA5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended APOA5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7434506
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7427942
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7438598
Quantity 100 μL
Datasheet Datasheet

Recommended APOA5 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN6973943
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963557
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6999564
Quantity 96 tests
Datasheet Datasheet

Recommended APOA5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1345336
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7273849
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5853437
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our APOA5 Products

Lightbourne, Wolska, Abel, Rother, Walter, Kushchayeva, Auh, Shamburek, Remaley, Muniyappa, Brown: "Apolipoprotein CIII and Angiopoietin-like Protein 8 are Elevated in Lipodystrophy and Decrease after Metreleptin." in: Journal of the Endocrine Society, Vol. 5, Issue 2, pp. bvaa191, (2021) (PubMed).

Zhu, Zhang, Zhou, Li, Li, Fang, Yang, Shan, Li, Chen, Zhou, Ye, Yu, Li, Cai, Liu, Zhang, Wang, Lai, Ruan, Sun, Zhang, Wang, Liu, Xu, Ling, Xu, Zhang, Lv, Yuan, Zhang, Zhang, Shi, Lai: "Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study." in: Journal of cellular and molecular medicine, Vol. 21, Issue 6, pp. 1106-1116, (2018) (PubMed).

Zheng, Yu, Xie, Zhao, Wu: "Apolipoprotein A5 regulates intracellular triglyceride metabolism in adipocytes." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 6771-6779, (2018) (PubMed).

Kim, Kim, Yoo, Lee, Chae, Lee, Lee: "A promoter variant of the APOA5 gene increases atherogenic LDL levels and arterial stiffness in hypertriglyceridemic patients." in: PLoS ONE, Vol. 12, Issue 12, pp. e0186693, (2018) (PubMed).

Ngaosuwan, Houngngam, Limpisook, Plengpanich, Khovidhunkit: "Apolipoprotein A-V is not a major determinant of triglyceride levels during human sepsis." in: Journal of critical care, Vol. 30, Issue 4, pp. 727-31, (2015) (PubMed).

van den Berg, Heemskerk, Geerling, van Klinken, Schaap, Bijland, Berbée, van Harmelen, Pronk, Schreurs, Havekes, Rensen, van Dijk: "Apolipoprotein A5 deficiency aggravates high-fat diet-induced obesity due to impaired central regulation of food intake." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 8, pp. 3354-62, (2013) (PubMed).

Guardiola, Alvaro, Vallvé, Rosales, Solà, Girona, Serra, Duran, Esteve, Masana, Ribalta: "APOA5 gene expression in the human intestinal tissue and its response to in vitro exposure to fatty acid and fibrate." in: Nutrition, metabolism, and cardiovascular diseases : NMCD, Vol. 22, Issue 9, pp. 756-62, (2012) (PubMed).

Hubacek, Wang, Skodová, Adámková, Vráblík, Horínek, Stulc, Ceska, Talmud: "APOA5 Ala315>Val, identified in patients with severe hypertriglyceridemia, is a common mutation with no major effects on plasma lipid levels." in: Clinical chemistry and laboratory medicine : CCLM / FESCC, Vol. 46, Issue 6, pp. 773-7, (2008) (PubMed).

Dorfmeister, Zeng, Dichlberger, Nilsson, Schaap, Hubacek, Merkel, Cooper, Lookene, Putt, Whittall, Lee, Lins, Delsaux, Nierman, Kuivenhoven, Kastelein, Vrablik, Olivecrona, Schneider, Heeren et al.: "Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding. ..." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 10, pp. 1866-71, (2008) (PubMed).

Corella, Lai, Demissie, Cupples, Manning, Tucker, Ordovas: "APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study." in: Journal of molecular medicine (Berlin, Germany), Vol. 85, Issue 2, pp. 119-28, (2007) (PubMed).

Synonyms and alternative names related to APOA5

apolipoprotein A5 (APOA5), apolipoprotein A-V (Apoa5), apolipoprotein A5 (Apoa5), apolipoprotein A5 L homeolog (apoa5.L), apolipoprotein A5 (apoa5), 1300007O05Rik, apo-AV, apoA-V, apoa-v, APOA5, APOAV, Apoav, apoav, MGC140487, RAP3, rap3

Protein level used designations for APOA5

  • apo-AV
  • apolipoprotein A5
  • regeneration-associated protein 3
  • apoA-V
  • apolipoprotein AV
  • apolipoprotein A-V
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