APLP2 产品
(Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))
Categories
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
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Featured APLP2 Categories
APLP2 抗体
High quality antibodies with extensive validation data.
APLP2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
APLP2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended APLP2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN2855243
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7426694
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7144051
Quantity
100 μL
Datasheet
Datasheet
Recommended APLP2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964811
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953687
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380928
Quantity
96 tests
Datasheet
Datasheet
Recommended APLP2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7273823
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345324
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345326
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our APLP2 Products
: "The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 35, Issue 4, pp. 655-66, (2015) (PubMed).: "Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other." in: The Journal of biological chemistry, Vol. 290, Issue 30, pp. 18609-20, (2015) (PubMed).
: "Abnormal platelet amyloid-? protein precursor (A?PP) metabolism in Alzheimer's disease: identification and characterization of a new A?PP isoform as potential biomarker." in: Journal of Alzheimer's disease : JAD, Vol. 35, Issue 2, pp. 285-95, (2013) (PubMed).
: "Amyloid precursor-like protein 2 increases the endocytosis, instability, and turnover of the H2-K(d) MHC class I molecule." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 3, pp. 1978-87, (2008) (PubMed).
Synonyms and alternative names related to APLP2
suppression of tumorigenicity 14 (ST14), amyloid beta precursor like protein 2 (APLP2), amyloid beta (A4) precursor-like protein 2 (Aplp2), amyloid beta precursor like protein 2 (Aplp2), amyloid beta (A4) precursor-like protein 2 S homeolog (aplp2.S), amyloid beta (A4) precursor-like protein 2 (aplp2), amyloid beta (A4) precursor-like protein 2 L homeolog (aplp2.L), amyloid beta precursor like protein 2 (aplp2), AI790698, APLP-2, APLP2, aplp2 A, aplp2 B, APPH, Apph, APPL2, CDEBP, HAI, MGC86389, MT-SP1, MTSP1, PRSS14, si:dkey-11k4.3, SNC19, TADG15, TMPRSS14, WALPLP2Protein level used designations for APLP2
- membrane-type serine protease 1
- prostamin
- serine protease 14
- serine protease TADG-15
- suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
- suppressor of tumorigenicity 14 protein
- tumor associated differentially expressed gene 15 protein
- tumor-associated differentially-expressed gene 15 protein
- CDEI box-binding protein
- amyloid precursor protein homolog HSD-2
- amyloid-like protein 2
- CDEBP
- Amyloid protein precursor-like protein 2
- amyloid beta (A4) precursor-like protein 2-like
- sperm membrane protein (YWK-II)
- sperm membrane protein YWK-II
- amyloid beta (A4) precursor-like protein 2
- amyloid-beta-like protein B
- suppression of tumorigenicity 14
- amyloid-like protein 2-like
- amyloid-beta-like protein A
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