APEX1 抗体
(Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene\; all encode the same protein. [provided by RefSeq, Jul 2008].
recommended
recommended
APEX1 适用: 人, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1H9 unconjugated
recommended
APEX1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7A2G7 unconjugated
APEX1 抗体 by Grade
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APEX1 抗体 by 抗体来源
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APEX1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal APEX1 抗体. Click on a link to go to the corresponding products.
Popular APEX1 抗体
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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (6)
Cat. No.
ABIN513392
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey
Application
WB, IHC, IHC (p)
Validations
- (8)
Cat. No.
ABIN1490625
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC, FACS
Validations
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Cat. No.
ABIN5611191
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IF, IP
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Cat. No.
ABIN947565
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
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Cat. No.
ABIN3015421
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (7)
Cat. No.
ABIN3043785
Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IF, IHC (p)
Validations
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Cat. No.
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Quantity
200 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC (p)
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Cat. No.
ABIN3181880
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC, IF, ICC
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Cat. No.
ABIN6259977
Quantity
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Datasheet
Datasheet
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Application
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Validations
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Cat. No.
ABIN6136981
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IF, ChIP, ICC, IP, Neut
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- (5)
Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC, ChIP
Validations
- (3)
Cat. No.
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Quantity
100 μg
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN184704
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN1490626
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Latest Publications for our APEX1 抗体
: "Targeting Histone Chaperone FACT Complex Overcomes 5-Fluorouracil Resistance in Colon Cancer." in: Molecular cancer therapeutics, Vol. 19, Issue 1, pp. 258-269, (2020) (PubMed).: "The long noncoding RNA ROCKI regulates inflammatory gene expression." in: The EMBO journal, Vol. 38, Issue 8, (2019) (PubMed).
: "Endonuclease and redox activities of human apurinic/apyrimidinic endonuclease 1 have distinctive and essential functions in IgA class switch recombination." in: The Journal of biological chemistry, Vol. 294, Issue 13, pp. 5198-5207, (2019) (PubMed).
: "The Molecular Chaperone Heat Shock Protein 70 Controls Liver Cancer Initiation and Progression by Regulating Adaptive DNA Damage and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated ..." in: Molecular and cellular biology, Vol. 39, Issue 9, (2019) (PubMed).
: "Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma." in: Oncotarget, Vol. 10, Issue 3, pp. 383-394, (2019) (PubMed).
: "Inactivation of XPF Sensitizes Cancer Cells to Gemcitabine." in: Journal of nucleic acids, Vol. 2019, pp. 6357609, (2019) (PubMed).
: "APE1 and NPM1 protect cancer cells from platinum compounds cytotoxicity and their expression pattern has a prognostic value in TNBC." in: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 309, (2019) (PubMed).
: "The endonuclease APE1 processes miR-92b formation, thereby regulating expression of the tumor suppressor LDLR in cervical cancer cells." in: Therapeutic advances in medical oncology, Vol. 11, pp. 1758835919855859, (2019) (PubMed).
: "ATP Binding Cassette Transporter A1 is Involved in Extracellular Secretion of Acetylated APE1/Ref-1." in: International journal of molecular sciences, Vol. 20, Issue 13, (2019) (PubMed).
: "Decreased APE-1 by Nitroxoline Enhances Therapeutic Effect in a Temozolomide-resistant Glioblastoma: Correlation with Diffusion Weighted Imaging." in: Scientific reports, Vol. 9, Issue 1, pp. 16613, (2019) (PubMed).
Aliases for APEX1 抗体
apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1) 抗体APEX nuclease (multifunctional DNA repair enzyme) 1 (apex1) 抗体
APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog (apex1.L) 抗体
DNA-(apurinic or apyrimidinic site) lyase (CNG03640) 抗体
DNA-(apurinic or apyrimidinic site) lyase (CNH01280) 抗体
DNA-(apurinic or apyrimidinic site) lyase (nth) 抗体
DNA-(apurinic or apyrimidinic site) lyase (Spirs_4119) 抗体
DNA-(apurinic or apyrimidinic site) lyase (Palpr_0103) 抗体
apurinic/apyrimidinic endodeoxyribonuclease 1 (Apex1) 抗体
apurinic/apyrimidinic endonuclease 1 (Apex1) 抗体
APE 抗体
APE1 抗体
APEN 抗体
APEX 抗体
Apex 抗体
apex1 抗体
apex1a 抗体
APX 抗体
BAP1 抗体
HAP1 抗体
hm:zehn1532 抗体
MGC76280 抗体
MGC78928 抗体
MGC79645 抗体
REF-1 抗体
Ref-1 抗体
REF1 抗体
wu:fc13d11 抗体
zgc:66204 抗体
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