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APC1 产品

(Anaphase Promoting Complex Subunit 1 (ANAPC1))

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This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011].

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Featured APC1 Categories

APC1 抗体

High quality antibodies with extensive validation data.

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Latest Publications for our APC1 Products

Spurlock, Tossberg, Olsen, Aune: "Cutting Edge: Chronic NF-κB Activation in CD4+ T Cells in Rheumatoid Arthritis Is Genetically Determined by HLA Risk Alleles." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 791-5, (2015) (PubMed).

Schiffman, Rodriguez, Chen, Wacholder, Herrero, Hildesheim, Desalle, Befano, Yu, Safaeian, Sherman, Morales, Guillen, Alfaro, Hutchinson, Solomon, Castle, Burk: "A population-based prospective study of carcinogenic human papillomavirus variant lineages, viral persistence, and cervical neoplasia." in: Cancer research, Vol. 70, Issue 8, pp. 3159-69, (2010) (PubMed).

Davoli, Denchi, de Lange: "Persistent telomere damage induces bypass of mitosis and tetraploidy." in: Cell, Vol. 141, Issue 1, pp. 81-93, (2010) (PubMed).

Kraft, Herzog, Gieffers, Mechtler, Hagting, Pines, Peters: "Mitotic regulation of the human anaphase-promoting complex by phosphorylation." in: The EMBO journal, Vol. 22, Issue 24, pp. 6598-609, (2003) (PubMed).

Jörgensen, Gräslund, Betz, Ståhl, Larsson, Höög: "Characterisation of the human APC1, the largest subunit of the anaphase-promoting complex." in: Gene, Vol. 262, Issue 1-2, pp. 51-9, (2001) (PubMed).

Synonyms and alternative names related to APC1

anaphase promoting complex subunit 1 (ANAPC1), anaphase promoting complex subunit 1 (Anapc1), anaphase promoting complex subunit 1 (CC1G_09696), anaphase promoting complex subunit 1 (anapc1), E3 ubiquitin ligase (EMB2771), 2610021O03Rik, AI047775, AI853536, APC1, Apc1, AW547281, DDBDRAFT_0186456, DDBDRAFT_0234263, DDB_0186456, DDB_0234263, EMBRYO DEFECTIVE 2771, MCPR, Mcpr, MOP10.10, MOP10_10, TSG24, tsg24

Protein level used designations for APC1

  • anaphase-promoting complex 1 (meiotic checkpoint regulator)
  • anaphase-promoting complex subunit 1
  • cyclosome subunit 1
  • mitotic checkpoint regulator
  • testis-specific gene 24 protein
  • anaphase promoting complex subunit 1
  • meiotic check point regulator
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