APC 抗体
(Adenomatous Polyposis Coli (APC))
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008].
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APC 抗体 by 适用
Find APC 抗体 for a variety of species such as anti-Human APC, anti-Mouse APC, anti-Rat APC. The species listed below are among those available. Click on a link to go to the corresponding products.
APC 抗体 by 抗体来源
Find APC 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
APC 抗体 by 克隆形成能力
Find available monoclonal or polyclonal APC 抗体. Click on a link to go to the corresponding products.
APC 抗体 by 克隆
Find APC 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular APC 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7439342
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN1678690
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7439345
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, PLA
Validations
- (3)
Cat. No.
ABIN559888
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6255083
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN702550
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7184577
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7127341
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7244711
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF
Validations
- (2)
Cat. No.
ABIN3183309
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (2)
Cat. No.
ABIN513388
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN7265452
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Cow, Human, Pig, Rat
Application
WB, IHC, IF, IC
Validations
- (3)
Cat. No.
ABIN7294930
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (1)
Cat. No.
ABIN7434812
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, FACS, Coat
Validations
- (1)
Cat. No.
ABIN6939658
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our APC 抗体
: "Microglia permit climbing fiber elimination by promoting GABAergic inhibition in the developing cerebellum." in: Nature communications, Vol. 9, Issue 1, pp. 2830, (2018) (PubMed).: "Promoter methylation status of tumor suppressor genes and inhibition of expression of DNA methyltransferase 1 in non-small cell lung cancer." in: Experimental biology and medicine (Maywood, N.J.), Vol. 241, Issue 14, pp. 1531-9, (2017) (PubMed).
: "Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis." in: Oncogene, (2016) (PubMed).
: "Genetic reconstitution of tumorigenesis in primary intestinal cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 27, pp. 11127-32, (2013) (PubMed).
: "Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway." in: Journal of cell science, Vol. 121, Issue Pt 11, pp. 1793-802, (2008) (PubMed).
: "Cadherins, catenins and APC in pleural malignant mesothelioma." in: The Journal of pathology, Vol. 201, Issue 3, pp. 355-62, (2003) (PubMed).
Aliases for APC 抗体
APC, WNT signaling pathway regulator (APC) 抗体adenomatous polyposis coli (apc) 抗体
adenomatous polyposis coli protein, putative (Smp_139190) 抗体
adenomatosis polyposis coli (Apc) 抗体
APC, WNT signaling pathway regulator (Apc) 抗体
adenomatous polyposis coli L homeolog (apc.L) 抗体
AI047805 抗体
APC1 抗体
AU020952 抗体
AW124434 抗体
BTPS2 抗体
CC1 抗体
dp2 抗体
DP2 抗体
dp2.5 抗体
DP2.5 抗体
dp3 抗体
DP3 抗体
fap 抗体
fpc 抗体
GS 抗体
mAPC 抗体
Min 抗体
PPP1R46 抗体
RATAPC 抗体
xapc 抗体
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