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- 抗原 See all YAP1 抗体
- YAP1 (Yes-Associated Protein 1 (YAP1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This YAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 原理
- YAP1 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human YAP1 expressed in E. Coli.
- 克隆位点
- 1A12
- 亚型
- IgG1
- Top Product
- Discover our top product YAP1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation." in: Genes & development, Vol. 23, Issue 23, pp. 2729-41, (2009) (PubMed).
: "YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway." in: Nature cell biology, Vol. 11, Issue 12, pp. 1444-50, (2009) (PubMed).
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YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation." in: Genes & development, Vol. 23, Issue 23, pp. 2729-41, (2009) (PubMed).
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- 抗原
- YAP1 (Yes-Associated Protein 1 (YAP1))
- 别名
- YAP1 (YAP1 产品)
- 背景
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Description: This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
Aliases: YAP, YKI, YAP2, YAP65
- 基因ID
- 10413
- HGNC
- 10413
- UniProt
- P46937
- 途径
- MAPK Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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