Ubiquitin B 抗体
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- 抗原 See all Ubiquitin B (UBB) 抗体
- Ubiquitin B (UBB)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Ubiquitin B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 原理
- UBB Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human UBB expressed in E. Coli.
- 克隆位点
- 3C12
- 亚型
- IgG1
- Top Product
- Discover our top product UBB Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Lysine acetylation targets protein complexes and co-regulates major cellular functions." in: Science (New York, N.Y.), Vol. 325, Issue 5942, pp. 834-40, (2009) (PubMed).
: "The emerging complexity of protein ubiquitination." in: Biochemical Society transactions, Vol. 37, Issue Pt 5, pp. 937-53, (2009) (PubMed).
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Lysine acetylation targets protein complexes and co-regulates major cellular functions." in: Science (New York, N.Y.), Vol. 325, Issue 5942, pp. 834-40, (2009) (PubMed).
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- 抗原
- Ubiquitin B (UBB)
- 别名
- UBB (UBB 产品)
- 别名
- AL033289 antibody, Rps27a antibody, Uba52 antibody, Ubb2 antibody, Ubc antibody, UBC antibody, Ubiquitin antibody, UBB antibody, Ubi-p63E antibody, im:6892314 antibody, si:ch211-202a12.3 antibody, ubc antibody, zUBC antibody, zgc:172187 antibody, ubiquitin B antibody, ubiquitin C antibody, UBB antibody, Ubb antibody, UBC antibody, ubb antibody
- 背景
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Description: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
Aliases: UBC, UBA52, RPS27A
- 分子量
- 26kDa
- 基因ID
- 7314
- HGNC
- 7314
- UniProt
- P0CG47
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, Autophagy, EGFR Downregulation, Ubiquitin Proteasome Pathway
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