TGFB1 抗体 (AA 62-195)
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- 抗原 See all TGFB1 抗体
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
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抗原表位
- AA 62-195
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TGFB1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- 原理
- TGFb1 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human TGFb1 (AA: 62-195) expressed in E. Coli.
- 克隆位点
- 7F6
- 亚型
- IgG1
- Top Product
- Discover our top product TGFB1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Effect of ultrasound irradiation on α-SMA and TGF-β1 expression in human dermal fibroblasts." in: The Kobe journal of medical sciences, Vol. 56, Issue 6, pp. E242-52, (2011) (PubMed).
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Effect of ultrasound irradiation on α-SMA and TGF-β1 expression in human dermal fibroblasts." in: The Kobe journal of medical sciences, Vol. 56, Issue 6, pp. E242-52, (2011) (PubMed).
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- 抗原
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
- 别名
- TGFb1 (TGFB1 产品)
- 背景
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Description: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease
Aliases: CED, LAP, DPD1, TGFB, TGFbeta
- 分子量
- 44.3kDa
- 基因ID
- 7040
- HGNC
- 7040
- UniProt
- P01137
- 途径
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
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