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RAP1A 抗体

RAP1A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5F8 unconjugated
产品编号 ABIN969561
发货至: 中国
  • 抗原 See all RAP1A 抗体
    RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
    适用
    • 47
    • 47
    • 17
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 57
    • 4
    小鼠
    克隆类型
    • 58
    • 3
    单克隆
    标记
    • 25
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
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    This RAP1A antibody is un-conjugated
    应用范围
    • 48
    • 23
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    原理
    RAP1A Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human RAP1A expressed in E. Coli.
    克隆位点
    5F8
    亚型
    IgG1
    Top Product
    Discover our top product RAP1A Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Severson, Lee, Capaldo, Nusrat, Parkos: "Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1916-25, (2009) (PubMed).

    Dao, Dupuy, Gavet, Caron, de Gunzburg: "Dynamic changes in Rap1 activity are required for cell retraction and spreading during mitosis." in: Journal of cell science, Vol. 122, Issue Pt 16, pp. 2996-3004, (2009) (PubMed).

  • 抗原
    RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
    别名
    RAP1A (RAP1A 产品)
    别名
    KREV-1 antibody, KREV1 antibody, RAP1 antibody, SMGP21 antibody, AI848598 antibody, G-22K antibody, Krev-1 antibody, Rap1 antibody, RAP-1A antibody, rap 1A antibody, wu:fc66g06 antibody, zgc:86676 antibody, krev-1 antibody, krev1 antibody, rap1 antibody, RAP1A, member of RAS oncogene family antibody, RAS-related protein 1a antibody, RAP1A, member of RAS oncogene family a antibody, RAP1A, member of RAS oncogene family L homeolog antibody, RAP1A antibody, Rap1a antibody, rap1aa antibody, rap1a.L antibody
    背景

    Description: The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50 % amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

    Aliases: RAP1, KREV1, KREV-1, SMGP21

    分子量
    21kDa
    基因ID
    5906
    HGNC
    5906
    UniProt
    P62834
    途径
    TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
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