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- 抗原 See all PDX1 抗体
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PDX1 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- PDX1 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human PDX1 expressed in E. Coli.
- 克隆位点
- 2G12
- 亚型
- IgG1
- Top Product
- Discover our top product PDX1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Aberrant expression of TFF1, TFF2, and PDX1 and their diagnostic value in lobular endocervical glandular hyperplasia." in: American journal of clinical pathology, Vol. 135, Issue 2, pp. 253-61, (2011) (PubMed).
: "Reduced expression of PDX-1 is associated with decreased beta cell function in chronic pancreatitis." in: Pancreas, Vol. 39, Issue 6, pp. 856-62, (2010) (PubMed).
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Aberrant expression of TFF1, TFF2, and PDX1 and their diagnostic value in lobular endocervical glandular hyperplasia." in: American journal of clinical pathology, Vol. 135, Issue 2, pp. 253-61, (2011) (PubMed).
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- 抗原
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- 别名
- PDX1 (PDX1 产品)
- 别名
- GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
- 背景
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Description: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Aliases: GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1
- 分子量
- 30.8kDa
- 基因ID
- 3651
- HGNC
- 3651
- UniProt
- P52945
- 途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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