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NEFL 抗体

NEFL 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1H3 unconjugated
产品编号 ABIN969548
发货至: 中国
  • 抗原 See all NEFL 抗体
    NEFL (Neurofilament, Light Polypeptide (NEFL))
    适用
    • 73
    • 51
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    • 1
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    宿主
    • 58
    • 34
    • 8
    • 1
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    小鼠
    克隆类型
    • 62
    • 41
    单克隆
    标记
    • 64
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    This NEFL antibody is un-conjugated
    应用范围
    • 57
    • 39
    • 32
    • 22
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    • 11
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    NEFL Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human NEFL expressed in E. Coli.
    克隆位点
    1H3
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Lee, Kim, Chung, Kim, Kwon, Min, Chang: "The effect of rod domain A148V mutation of neurofilament light chain on filament formation." in: BMB reports, Vol. 41, Issue 12, pp. 868-74, (2009) (PubMed).

    Abe, Numakura, Saito, Koide, Oka, Honma, Kishikawa, Hayasaka: "Neurofilament light chain polypeptide gene mutations in Charcot-Marie-Tooth disease: nonsense mutation probably causes a recessive phenotype." in: Journal of human genetics, Vol. 54, Issue 2, pp. 94-7, (2009) (PubMed).

  • 抗原
    NEFL (Neurofilament, Light Polypeptide (NEFL))
    别名
    NEFL (NEFL 产品)
    别名
    NEFL antibody, nefl antibody, zgc:136626 antibody, AI847934 antibody, CMT2E antibody, NF-L antibody, NF68 antibody, Nfl antibody, CMT1F antibody, NFL antibody, XNF-L antibody, neurofilament light antibody, neurofilament, light polypeptide antibody, neurofilament, light polypeptide b antibody, neurofilament, light L homeolog antibody, NEFL antibody, neflb antibody, Nefl antibody, nefl.L antibody
    背景

    Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

    Aliases: NFL, NF-L, NF68, CMT1F, CMT2E

    分子量
    62kDa
    基因ID
    4747
    HGNC
    4747
    UniProt
    P07196
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