NEFL 抗体
-
- 抗原 See all NEFL 抗体
- NEFL (Neurofilament, Light Polypeptide (NEFL))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This NEFL antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- NEFL Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human NEFL expressed in E. Coli.
- 克隆位点
- 1H3
- 亚型
- IgG1
-
-
- 应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
The effect of rod domain A148V mutation of neurofilament light chain on filament formation." in: BMB reports, Vol. 41, Issue 12, pp. 868-74, (2009) (PubMed).
: "Neurofilament light chain polypeptide gene mutations in Charcot-Marie-Tooth disease: nonsense mutation probably causes a recessive phenotype." in: Journal of human genetics, Vol. 54, Issue 2, pp. 94-7, (2009) (PubMed).
: "
-
The effect of rod domain A148V mutation of neurofilament light chain on filament formation." in: BMB reports, Vol. 41, Issue 12, pp. 868-74, (2009) (PubMed).
-
- 抗原
- NEFL (Neurofilament, Light Polypeptide (NEFL))
- 别名
- NEFL (NEFL 产品)
- 别名
- NEFL antibody, nefl antibody, zgc:136626 antibody, AI847934 antibody, CMT2E antibody, NF-L antibody, NF68 antibody, Nfl antibody, CMT1F antibody, NFL antibody, XNF-L antibody, neurofilament light antibody, neurofilament, light polypeptide antibody, neurofilament, light polypeptide b antibody, neurofilament, light L homeolog antibody, NEFL antibody, neflb antibody, Nefl antibody, nefl.L antibody
- 背景
-
Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Aliases: NFL, NF-L, NF68, CMT1F, CMT2E
- 分子量
- 62kDa
- 基因ID
- 4747
- HGNC
- 4747
- UniProt
- P07196
-