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NCK1 抗体

NCK1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5B7 unconjugated
产品编号 ABIN969545
发货至: 中国
  • 抗原 See all NCK1 抗体
    NCK1 (NCK Adaptor Protein 1 (NCK1))
    适用
    • 73
    • 25
    • 22
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    • 2
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    • 1
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    宿主
    • 66
    • 6
    • 1
    小鼠
    克隆类型
    • 60
    • 13
    单克隆
    标记
    • 32
    • 7
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    This NCK1 antibody is un-conjugated
    应用范围
    • 52
    • 31
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    • 7
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    • 2
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    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    原理
    NCK1 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human NCK1 expressed in E. Coli.
    克隆位点
    5B7
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Preisinger, Kolch: "The Bcr-Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway." in: Cellular signalling, Vol. 22, Issue 5, pp. 848-56, (2010) (PubMed).

    Blasutig, New, Thanabalasuriar, Dayarathna, Goudreault, Quaggin, Li, Gruenheid, Jones, Pawson: "Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization." in: Molecular and cellular biology, Vol. 28, Issue 6, pp. 2035-46, (2008) (PubMed).

  • 抗原
    NCK1 (NCK Adaptor Protein 1 (NCK1))
    别名
    NCK1 (NCK1 产品)
    别名
    NCK antibody, NCKalpha antibody, nck-1 antibody, NCK1 antibody, 6330586M15Rik antibody, D230010O13Rik antibody, Nck antibody, Nck-1 antibody, Nck1 antibody, nck antibody, nck1-a antibody, nck1-b antibody, nckalpha antibody, NCK adaptor protein 1 antibody, non-catalytic region of tyrosine kinase adaptor protein 1 antibody, NCK adaptor protein 1b antibody, NCK adaptor protein 1 L homeolog antibody, NCK1 antibody, Nck1 antibody, nck1b antibody, nck1.L antibody
    背景

    Description: The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.

    Aliases: NCK, nck-1, NCKalpha

    分子量
    47kDa
    基因ID
    4690
    HGNC
    4690
    UniProt
    P16333
    途径
    TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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