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- 抗原 See all LRP5 抗体
- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LRP5 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- LRP5 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human LRP5 expressed in E. Coli.
- 克隆位点
- 2B11
- 亚型
- IgG1
- Top Product
- Discover our top product LRP5 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Low-density lipoprotein receptor-related protein 5 (LRP5) variation in fracture prone children." in: Bone, Vol. 46, Issue 4, pp. 940-5, (2010) (PubMed).
: "A1330V variant of the low-density lipoprotein receptor-related protein 5 (LRP5) gene decreases Wnt signaling and affects the total body bone mineral density in Japanese women." in: Endocrine journal, Vol. 56, Issue 4, pp. 625-31, (2009) (PubMed).
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Low-density lipoprotein receptor-related protein 5 (LRP5) variation in fracture prone children." in: Bone, Vol. 46, Issue 4, pp. 940-5, (2010) (PubMed).
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- 抗原
- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
- 别名
- LRP5 (LRP5 产品)
- 别名
- Xlrp5 antibody, bmnd1 antibody, evr1 antibody, evr4 antibody, hbm antibody, lr3 antibody, lrp5-A antibody, lrp7 antibody, oppg antibody, ops antibody, opta1 antibody, vbch2 antibody, LRP5 antibody, LRP6 antibody, BMND1 antibody, EVR1 antibody, EVR4 antibody, HBM antibody, LR3 antibody, LRP7 antibody, OPPG antibody, OPS antibody, OPTA1 antibody, VBCH2 antibody, mKIAA4142 antibody, low-density lipoprotein receptor-related protein 5 antibody, LDL receptor related protein 5 antibody, LDL receptor related protein 5 L homeolog antibody, low density lipoprotein receptor-related protein 5 antibody, LDL receptor related protein 5 like antibody, LOC100147353 antibody, LRP5 antibody, lrp5.L antibody, lrp5 antibody, Lrp5 antibody, LRP5L antibody
- 背景
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Description: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
Aliases: HBM, LR3, OPS, EVR1, EVR4, LRP7, OPPG, BMND1, OPTA1, VBCH2
- 分子量
- 179kDa
- 基因ID
- 4041
- HGNC
- 4041
- UniProt
- O75197
- 途径
- WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
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