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Lp(a) 抗体 (AA 1823-2013)

Lp(a) 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 4H1 unconjugated
产品编号 ABIN969533
发货至: 中国
  • 抗原
    Lp(a) (Lipoprotein (Lp(a)))
    抗原表位
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1823-2013
    适用
    • 27
    • 1
    宿主
    • 13
    • 11
    • 3
    小鼠
    克隆类型
    • 16
    • 11
    单克隆
    标记
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Lp(a) antibody is un-conjugated
    应用范围
    • 8
    • 8
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    原理
    LPA Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human LPA (AA: 1823-2013) expressed in E. Coli.
    克隆位点
    4H1
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Nicholls, Tang, Scoffone, Brennan, Hartiala, Allayee, Hazen: "Lipoprotein(a) levels and long-term cardiovascular risk in the contemporary era of statin therapy." in: Journal of lipid research, Vol. 51, Issue 10, pp. 3055-61, (2010) (PubMed).

    Rodger, Le Gal, Carrier, Betancourt, Kahn, Wells, Anderson, Lacut, Chagnon, Solymoss, Crowther, Perrier, White, Vickars, Ramsay, Kovacs: "Serum lipoprotein (a) levels in patients with first unprovoked venous thromboembolism is not associated with subsequent risk of recurrent VTE." in: Thrombosis research, Vol. 126, Issue 3, pp. 222-6, (2010) (PubMed).

  • 抗原
    Lp(a) (Lipoprotein (Lp(a)))
    别名
    LPA
    背景

    Description: The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence.

    Aliases: LP, AK38, APOA

    分子量
    501kDa
    基因ID
    4018
    HGNC
    4018
    UniProt
    P08519
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