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Glypican 3 抗体

GPC3 适用: 人, 小鼠 WB, FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 9C2 unconjugated
产品编号 ABIN969523
发货至: 中国
  • 抗原 See all Glypican 3 (GPC3) 抗体
    Glypican 3 (GPC3)
    适用
    • 143
    • 49
    • 46
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 89
    • 54
    • 1
    小鼠
    克隆类型
    • 75
    • 68
    • 1
    单克隆
    标记
    • 58
    • 12
    • 7
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    • 5
    • 5
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    • 5
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    • 2
    • 1
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    This Glypican 3 antibody is un-conjugated
    应用范围
    • 81
    • 78
    • 63
    • 44
    • 35
    • 26
    • 16
    • 16
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human GPC3 expressed in E. coli.
    克隆位点
    9C2
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Zittermann, Capurro, Shi, Filmus: "Soluble glypican 3 inhibits the growth of hepatocellular carcinoma in vitro and in vivo." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 6, pp. 1291-301, (2010) (PubMed).

    Takai, Ashihara, Ishiguro, Terashima, Watanabe, Kato, Suzuki: "Involvement of glypican-3 in the recruitment of M2-polarized tumor-associated macrophages in hepatocellular carcinoma." in: Cancer biology & therapy, Vol. 8, Issue 24, pp. 2329-38, (2010) (PubMed).

  • 抗原
    Glypican 3 (GPC3)
    别名
    GPC3 (GPC3 产品)
    别名
    GPC3 antibody, sgb antibody, dgsx antibody, sdys antibody, sgbs antibody, oci-5 antibody, sgbs1 antibody, DGSX antibody, GTR2-2 antibody, MXR7 antibody, OCI-5 antibody, SDYS antibody, SGB antibody, SGBS antibody, SGBS1 antibody, Glypican-3 antibody, glypican 3 antibody, gpc3 antibody, GPC3 antibody, Gpc3 antibody
    背景

    Description: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

    Aliases: SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2

    分子量
    65.5 kDa
    基因ID
    2719
    HGNC
    2719
    途径
    Glycosaminoglycan Metabolic Process
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