Doublecortin 抗体 (AA 362-411)
(1 reference)-
- 抗原 See all Doublecortin (DCX) 抗体
- Doublecortin (DCX)
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抗原表位
- AA 362-411
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Doublecortin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- DCX Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human DCX (AA: 362-411) expressed in E. Coli.
- 克隆位点
- 2G5
- 亚型
- IgG1
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anti-Doublecortin (DCX) (AA 232-242) antibody
Verified DCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 362-411) antibodyDCX 适用: 人 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Doublecortin (DCX) (AA 1-360) antibodyDCX 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Doublecortin (DCX) (AA 69-81) antibodyVerified DCX 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 108-360) antibodyDCX 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 11-360) antibodyDCX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (Ser30) antibodyDCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (pSer335) antibodyDCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 240-360) antibodyDCX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) antibodyDCX 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 12, pp. 4276-87, (2009) (PubMed).
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: "MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 12, pp. 4276-87, (2009) (PubMed).
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- 抗原
- Doublecortin (DCX)
- 别名
- DCX (DCX 产品)
- 别名
- DCX antibody, DBCN antibody, DC antibody, LISX antibody, SCLH antibody, XLIS antibody, Dbct antibody, 18C15.5 antibody, doublecortin antibody, DCX antibody, Dcx antibody
- 背景
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Description: This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain" syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: DC, DBCN, LISX, SCLH, XLIS
- 分子量
- 49.3kDa
- 基因ID
- 1641
- HGNC
- 1641
- UniProt
- O43602
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