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CCL2 抗体

CCL2 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2D8 unconjugated
产品编号 ABIN969505
发货至: 中国
  • 抗原 See all CCL2 抗体
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    适用
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    宿主
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    小鼠
    克隆类型
    • 145
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    单克隆
    标记
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    This CCL2 antibody is un-conjugated
    应用范围
    • 143
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    原理
    CCL2 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human CCL2 expressed in E. Coli.
    克隆位点
    2D8
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Reine, Vuong, Rutkovskiy, Meen, Vaage, Jenssen, Kolset: "Serglycin in Quiescent and Proliferating Primary Endothelial Cells." in: PLoS ONE, Vol. 10, Issue 12, pp. e0145584, (2015) (PubMed).

    Semple, Kossmann, Morganti-Kossmann: "Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 30, Issue 3, pp. 459-73, (2010) (PubMed).

  • 抗原
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    别名
    CCL2 (CCL2 产品)
    别名
    GDCF-2 antibody, HC11 antibody, HSMCR30 antibody, MCAF antibody, MCP-1 antibody, MCP1 antibody, SCYA2 antibody, SMC-CF antibody, AI323594 antibody, JE antibody, Scya2 antibody, Sigje antibody, MCP-1A antibody, MCP1A antibody, C-C motif chemokine ligand 2 antibody, chemokine (C-C motif) ligand 2 antibody, C-C motif chemokine 2 antibody, CCL2 antibody, Ccl2 antibody, LOC101120093 antibody
    背景

    Description: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

    Aliases: HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30

    分子量
    11kDa
    基因ID
    6347
    HGNC
    6347
    UniProt
    P13500
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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