(2 references)-
- 抗原 See all PRTN3 抗体
- PRTN3 (Proteinase 3 (PRTN3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PRTN3 antibody is un-conjugated
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应用范围
- ELISA
- 原理
- Proteinase 3 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
- 克隆位点
- 3B4
- 亚型
- IgG2b
- Top Product
- Discover our top product PRTN3 Primary Antibody
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anti-Proteinase 3 (PRTN3) (AA 71-247) antibody
PRTN3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 88-98) antibodyVerified PRTN3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 24-249) antibodyPRTN3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 1-170) antibodyPRTN3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 228-256), (C-Term) antibodyPRTN3 适用: 人 WB 宿主: 兔 Polyclonal RB40945 unconjugated
anti-Proteinase 3 (PRTN3) (AA 1-256) antibodyPRTN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 1-256) antibodyPRTN3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 139-248) antibodyPRTN3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 76-125) antibodyPRTN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Proteinase 3 (PRTN3) (AA 28-170), (pArg3) antibodyPRTN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis." in: Blood, Vol. 110, Issue 12, pp. 4086-95, (2007) (PubMed).
: "Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism." in: Clinical and experimental immunology, Vol. 145, Issue 1, pp. 63-70, (2006) (PubMed).
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: "Proteinase 3, the Wegener autoantigen, is externalized during neutrophil apoptosis: evidence for a functional association with phospholipid scramblase 1 and interference with macrophage phagocytosis." in: Blood, Vol. 110, Issue 12, pp. 4086-95, (2007) (PubMed).
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- 抗原
- PRTN3 (Proteinase 3 (PRTN3))
- 别名
- Proteinase 3 (PRTN3 产品)
- 别名
- ela2 antibody, MGC132250 antibody, ACPA antibody, AGP7 antibody, C-ANCA antibody, CANCA antibody, MBN antibody, MBT antibody, NP-4 antibody, NP4 antibody, P29 antibody, PR-3 antibody, PR3 antibody, mPR3 antibody, proteinase 3 L homeolog antibody, proteinase 3 antibody, prtn3.L antibody, PRTN3 antibody, Prtn3 antibody
- 背景
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Description: Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Aliases: PRTN3, ACPA, CANCA
- 分子量
- 28kDa
- 基因ID
- 5657
- HGNC
- 5657
- UniProt
- P24158
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