MTDH 抗体
(2 references)-
- 抗原 See all MTDH 抗体
- MTDH (Metadherin (MTDH))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This MTDH antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- 原理
- Metadherin Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human Metadherin expressed in E. Coli.
- 克隆位点
- 2F11C3
- 亚型
- IgG1
- Top Product
- Discover our top product MTDH Primary Antibody
-
anti-Metadherin (MTDH) antibody
MTDH 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 101-270) antibodyMTDH 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-582) antibodyMTDH 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-582) antibodyMTDH 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 101-270) antibodyMTDH 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 1-260) antibodyMTDH 适用: 人 IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) (AA 131-230) antibodyMTDH 适用: 人 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Metadherin (MTDH) antibodyMTDH 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 2F11C3 unconjugated
-
- 应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
: "Identification of a novel protein, LYRIC, localized to tight junctions of polarized epithelial cells." in: Experimental cell research, Vol. 300, Issue 1, pp. 134-48, (2004) (PubMed).
: "Metadherin, a cell surface protein in breast tumors that mediates lung metastasis." in: Cancer cell, Vol. 5, Issue 4, pp. 365-74, (2004) (PubMed).
-
: "Identification of a novel protein, LYRIC, localized to tight junctions of polarized epithelial cells." in: Experimental cell research, Vol. 300, Issue 1, pp. 134-48, (2004) (PubMed).
-
- 抗原
- MTDH (Metadherin (MTDH))
- 别名
- Metadherin (MTDH 产品)
- 别名
- MGC75963 antibody, 2610103J23Rik antibody, 3D3 antibody, 3D3/Lyric antibody, AEG-1 antibody, AV353288 antibody, D8Bwg1112e antibody, Lyric antibody, AEG1 antibody, LYRIC antibody, LYRIC/3D3 antibody, metadherin antibody, mtdh antibody, MTDH antibody, Mtdh antibody
- 背景
-
Description: Metadherin (Metastasis adhesion protein), also known as MTDH, LYsine-RIch CEACAM1 co-isolated (LYRIC), is a novel protein that localizes with the tight junction proteins ZO-1 and occludin in polarized epithelial cells. At the tight junction, it acts not as a structural component, but is rather recruited during the maturation of the tight junction complex. Metadherin is overexpressed in breast cancer tissue and breast tumor xenografts, while much lower levels are expressed in normal breast tissue. Metadherin binds to lung vasculature, one of the four common sites of breast cancer metastasis, through a C-terminal segment in the extracellular domain, blocking this lung-homing domain with antibodies or inhibiting metadherin with siRNA has been reported to inhibit breast cancer metastasis.
Aliases: 3D3, AEG1, LYRIC, MTDH
- 分子量
- 64kDa
- 基因ID
- 92140
- HGNC
- 92140
- UniProt
- Q86UE4
- 途径
- Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
-
