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- 抗原 See all MATK 抗体
- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MATK antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 原理
- MATK Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human MATK expressed in E. Coli.
- 克隆位点
- 9D7
- 亚型
- IgG1
- Top Product
- Discover our top product MATK Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration." in: International journal of oncology, Vol. 21, Issue 1, pp. 197-205, (2002) (PubMed).
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Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration." in: International journal of oncology, Vol. 21, Issue 1, pp. 197-205, (2002) (PubMed).
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- 抗原
- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
- 别名
- MATK (MATK 产品)
- 别名
- si:ch211-63j24.2 antibody, CHK antibody, CTK antibody, HHYLTK antibody, HYL antibody, HYLTK antibody, Lsk antibody, Ntk antibody, Batk antibody, megakaryocyte-associated tyrosine kinase antibody, zinc finger RNA binding protein 2 antibody, matk antibody, MATK antibody, Matk antibody, ZFR2 antibody
- 背景
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Description: MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
Aliases: CHK, CTK
- 分子量
- 56kDa
- 基因ID
- 4145
- HGNC
- 4145
- UniProt
- P42679
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