电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

MCL-1 抗体

MCL1 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 8C6D4B1 unconjugated
产品编号 ABIN969485
发货至: 中国
  • 抗原 See all MCL-1 (MCL1) 抗体
    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
    适用
    • 148
    • 74
    • 66
    • 7
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    宿主
    • 139
    • 10
    • 2
    • 1
    小鼠
    克隆类型
    • 135
    • 19
    单克隆
    标记
    • 69
    • 11
    • 10
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MCL-1 antibody is un-conjugated
    应用范围
    • 120
    • 62
    • 49
    • 46
    • 27
    • 26
    • 21
    • 21
    • 8
    • 7
    • 7
    • 5
    • 4
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    原理
    MCL-1 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human MCL-1 expressed in E. Coli.
    克隆位点
    8C6D4B1
    亚型
    IgG1
    Top Product
    Discover our top product MCL1 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Richert, Schwertfeger, Ryder, Anderson: "An atlas of mouse mammary gland development." in: Journal of mammary gland biology and neoplasia, Vol. 5, Issue 2, pp. 227-41, (2001) (PubMed).

    MacLachlan, Hébert: "Statement concerning euthanasia and physician-assisted suicide. Ethics Committee of the College of Family Physicians of Canada." in: Canadian family physician Médecin de famille canadien, Vol. 46, pp. 254-6, 264-7, (2000) (PubMed).

  • 抗原
    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
    别名
    MCL-1 (MCL1 产品)
    别名
    BCL2L3 antibody, EAT antibody, MCL1-ES antibody, MCL1L antibody, MCL1S antibody, Mcl-1 antibody, TM antibody, bcl2-L-3 antibody, mcl1/EAT antibody, AW556805 antibody, mcl-1 antibody, fb72f02 antibody, wu:fb70a08 antibody, wu:fb72f02 antibody, zfMLP1 antibody, zfMcl-1a antibody, zgc:109835 antibody, zgc:109763 antibody, E3 antibody, E3-2 antibody, RNE3 antibody, RNU107 antibody, SNORA63A antibody, elF-4AII antibody, MCL1, BCL2 family apoptosis regulator antibody, myeloid cell leukemia sequence 1 antibody, MCL1, BCL2 family apoptosis regulator a antibody, MCL1, BCL2 family apoptosis regulator b antibody, small nucleolar RNA, H/ACA box 63 antibody, MCL1 antibody, Mcl1 antibody, mcl1a antibody, mcl1b antibody, SNORA63 antibody
    背景

    Description: Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that
    increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or
    exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related
    protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This
    monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.

    Aliases: EAT, MCL1L, MCL1S

    分子量
    37kDa
    基因ID
    4170
    HGNC
    4170
    UniProt
    Q07820
    途径
    MAPK Pathway
客服