Apoa5(ab) (AA 20-363) 抗体
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- 抗原
- Apoa5(ab)
- 抗原表位
- AA 20-363
- 适用
- 人
- 宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
- 应用范围
- ELISA, Western Blotting (WB)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human APOA5 (AA: 20-363) expressed in E. coli.
- 克隆位点
- 1G5G9(c)
- 亚型
- IgG1
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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- 抗原
- Apoa5(ab)
- 别名
- Apoa5 (ab)
- 背景
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Description: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70 % lower , concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
Aliases: RAP3, APOAV, APOA-V
- 基因ID
- 116519
- HGNC
- 116519
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