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WDR5 抗体

WDR5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7B11 unconjugated
产品编号 ABIN969456
发货至: 中国
  • 抗原 See all WDR5 抗体
    WDR5 (WD Repeat Domain 5 (WDR5))
    适用
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    • 34
    • 26
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    宿主
    • 58
    • 4
    • 1
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    小鼠
    克隆类型
    • 52
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    • 1
    单克隆
    标记
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    This WDR5 antibody is un-conjugated
    应用范围
    • 40
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    • 11
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
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    Western Blotting (WB), ELISA
    原理
    WDR5 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human WDR5 expressed in E. Coli.
    克隆位点
    7B11
    亚型
    IgG2b
    Top Product
    Discover our top product WDR5 Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Patel, Vought, Dharmarajan, Cosgrove: "A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex." in: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 32162-75, (2008) (PubMed).

    Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原
    WDR5 (WD Repeat Domain 5 (WDR5))
    别名
    WDR5 (WDR5 产品)
    别名
    BIG-3 antibody, SWD3 antibody, 2410008O07Rik antibody, AA408785 antibody, AA960360 antibody, Big antibody, Big-3 antibody, zgc:56591 antibody, zgc:76895 antibody, wu:fk47f04 antibody, wdr5-a antibody, MGC80538 antibody, wdr5-b antibody, MGC81485 antibody, big-3 antibody, swd3 antibody, xwdr5 antibody, WDR5B antibody, WD repeat domain 5 antibody, WD repeat domain 5 L homeolog antibody, WD repeat domain 5 S homeolog antibody, WDR5 antibody, Wdr5 antibody, wdr5 antibody, wdr5.L antibody, wdr5.S antibody
    背景

    Description: WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.

    Aliases: SWD3, BIG-3, WDR5

    分子量
    36.6kDa
    基因ID
    11091
    HGNC
    11091
    UniProt
    P61964
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