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- 抗原 See all TYRO3 抗体
- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TYRO3 antibody is un-conjugated
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应用范围
- ELISA
- 原理
- TYRO3 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant extracellular fragment of human TYRO3 fused with hIgGFc tag expressed in HEK293 cell line.
- 克隆位点
- 10E11
- 亚型
- IgG1
- Top Product
- Discover our top product TYRO3 Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway." in: Blood, Vol. 95, Issue 2, pp. 633-8, (2000) (PubMed).
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Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway." in: Blood, Vol. 95, Issue 2, pp. 633-8, (2000) (PubMed).
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- 抗原
- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
- 别名
- TYRO3 (TYRO3 产品)
- 别名
- TYRO3 antibody, brt antibody, byk antibody, dtk antibody, rse antibody, sky antibody, tif antibody, Xksy antibody, MGC145734 antibody, DKFZp469I0432 antibody, LOC100231598 antibody, BYK antibody, Dtk antibody, RSE antibody, Sky antibody, Tif antibody, Brt antibody, REK antibody, ksy antibody, xksy antibody, AI323366 antibody, Etk-2 antibody, Rse antibody, TYRO3 protein tyrosine kinase antibody, TYRO3 protein tyrosine kinase L homeolog antibody, TYRO3 protein tyrosine kinase 3 antibody, TYRO3 antibody, tyro3 antibody, Tyro3 antibody, tyro3.L antibody
- 背景
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Description: TYRO3: Tyrosine-protein kinase, also known as BYK, Brt, Dtk, Sky. Entrez Protein: NP_006284. It belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
Aliases: BYK, Brt, Dtk, RSE, Sky, Tif
- 分子量
- 96.9kDa
- 基因ID
- 7301
- HGNC
- 7301
- UniProt
- Q06418
- 途径
- RTK signaling
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