TRIM5 抗体
(3 references)-
- 抗原 See all TRIM5 抗体
- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TRIM5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 原理
- Trim5a Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human trim5 alpha expressed in E. Coli.
- 克隆位点
- 3B11H2
- 亚型
- IgG1
- Top Product
- Discover our top product TRIM5 Primary Antibody
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anti-Tripartite Motif Containing 5 (TRIM5) (N-Term) antibody
Verified TRIM5 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (N-Term) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (AA 1-493) antibodyTRIM5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (C-Term) antibodyTRIM5 适用: 人, 猴 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) antibodyTRIM5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (AA 35-84) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (AA 100-200) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (N-Term) antibodyTRIM5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 5 (TRIM5) (Middle Region 1) antibodyTRIM5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Retrovirus restriction by TRIM5alpha variants from Old World and New World primates." in: Journal of virology, Vol. 79, Issue 7, pp. 3930-7, (2005) (PubMed).
: "The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 29, pp. 10780-5, (2004) (PubMed).
: "The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys." in: Nature, Vol. 427, Issue 6977, pp. 848-53, (2004) (PubMed).
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: "Retrovirus restriction by TRIM5alpha variants from Old World and New World primates." in: Journal of virology, Vol. 79, Issue 7, pp. 3930-7, (2005) (PubMed).
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- 抗原
- TRIM5 (Tripartite Motif Containing 5 (TRIM5))
- 别名
- Trim5a (TRIM5 产品)
- 别名
- TRIM5 antibody, RNF88 antibody, TRIM5alpha antibody, EG667823 antibody, Gm8833 antibody, RGD1304579 antibody, tripartite motif containing 5 antibody, tripartite motif-containing 5 antibody, TRIM5 antibody, Trim5 antibody
- 背景
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Description: TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.
Aliases: RNF88, TRIM5alpha
- 基因ID
- 85363
- HGNC
- 85364
- UniProt
- Q9C035
- 途径
- Activation of Innate immune Response
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