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TNNI2 抗体

TNNI2 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2F12A11 unconjugated
产品编号 ABIN969441
发货至: 中国
  • 抗原 See all TNNI2 抗体
    TNNI2 (Fast Skeletal Troponin I (TNNI2))
    适用
    • 39
    • 18
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 30
    • 16
    • 2
    小鼠
    克隆类型
    • 31
    • 17
    单克隆
    标记
    • 28
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNNI2 antibody is un-conjugated
    应用范围
    • 39
    • 22
    • 15
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    原理
    TNNI2 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human TNNI2 expressed in E. Coli.
    克隆位点
    2F12A11
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

    Moran, Garriock, Miller, Heimark, Gregorio, Krieg: "Expression of the fast twitch troponin complex, fTnT, fTnI and fTnC, in vascular smooth muscle." in: Cell motility and the cytoskeleton, Vol. 65, Issue 8, pp. 652-61, (2008) (PubMed).

  • 抗原
    TNNI2 (Fast Skeletal Troponin I (TNNI2))
    别名
    TNNI2 (TNNI2 产品)
    别名
    AMCD2B antibody, DA2B antibody, FSSV antibody, fsTnI antibody, TnI-F4 antibody, TnI antibody, TNI antibody, hm:zehn0173 antibody, tnni2 antibody, tropI-1d antibody, zgc:86800 antibody, troponin I2, fast skeletal type antibody, troponin I type 2 (skeletal, fast) antibody, troponin I, fast skeletal muscle-like antibody, troponin I, skeletal, fast 2 antibody, troponin I type 2a (skeletal, fast), tandem duplicate 4 antibody, TNNI2 antibody, Tnni2 antibody, tnni2a.4 antibody
    背景

    Description: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

    Aliases: DA2B, FSSV, fsTnI, AMCD2B

    分子量
    21kDa
    基因ID
    7136
    HGNC
    7136
    UniProt
    P48788
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