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- 抗原 See all Src 抗体
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Src antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 原理
- SRC Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human SRC expressed in E. Coli.
- 克隆位点
- 1F11
- 亚型
- IgG1
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 22, pp. 6852-61, (2009) (PubMed).
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Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 22, pp. 6852-61, (2009) (PubMed).
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- 抗原
- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
- 别名
- SRC (Src 产品)
- 物质类
- Viral Protein
- 背景
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Description: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Aliases: ASV, SRC1, c-SRC, p60-Src
- 分子量
- 60kDa
- 基因ID
- 6714
- HGNC
- 6714
- UniProt
- P12931
- 途径
- JAK/STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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