(2 references)-
- 抗原 See all SNAIL (SNAI1) 抗体
- SNAIL (SNAI1)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SNAIL antibody is un-conjugated
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应用范围
- ELISA
- 原理
- SNAI1 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human SNAI1 expressed in E. Coli.
- 克隆位点
- 6D2
- 亚型
- IgG1
- Top Product
- Discover our top product SNAI1 Primary Antibody
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anti-SNAIL (SNAI1) (AA 1-100) antibody
SNAI1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (C-Term) antibodySNAI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (C-Term) antibodySNAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (N-Term) antibodySNAI1 适用: 人, 小鼠, 大鼠, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (AA 121-230) antibodySNAI1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G11 unconjugated
anti-SNAIL (SNAI1) (AA 1-264) antibodySNAI1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (AA 9-39), (N-Term) antibodySNAI1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01400 unconjugated
anti-SNAIL (SNAI1) antibodySNAI1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) antibodySNAI1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAIL (SNAI1) (pSer246) antibodySNAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression." in: Experimental cell research, Vol. 314, Issue 13, pp. 2448-53, (2008) (PubMed).
: "Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor." in: Molecular and cellular biology, Vol. 28, Issue 15, pp. 4772-81, (2008) (PubMed).
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: "Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression." in: Experimental cell research, Vol. 314, Issue 13, pp. 2448-53, (2008) (PubMed).
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- 抗原
- SNAIL (SNAI1)
- 别名
- SNAI1 (SNAI1 产品)
- 背景
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Description: Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells . Indeed, loss of E-cadherin expression is correlated with the invasive properties of some tumors and there is a considerable inverse correlation between Snail and E-cadherin mRNA levels in epithelial tumor cell lines . In addition, Snail blocks the cell cycle and confers resistance to cell death . Phosphorylation of Snail by GSK-3 and PAK1 regulates its stability, cellular localization and function .Tissue specificity: Expressed in a variety of tissues with the highest expression in kidney.
Aliases: SNA, SNAH, SLUGH2, dJ710H13.1, SNAI1
- 分子量
- 29kDa
- 基因ID
- 6615
- HGNC
- 6615
- UniProt
- O95863
- 途径
- Negative Regulation of intrinsic apoptotic Signaling
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