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SMC1A 抗体

SMC1A 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5B6 unconjugated
产品编号 ABIN969406
发货至: 中国
  • 抗原 See all SMC1A 抗体
    SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This SMC1A antibody is un-conjugated
    应用范围
    • 102
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    SMC1 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human SMC1 expressed in E. Coli.
    克隆位点
    5B6
    亚型
    IgG1
    Top Product
    Discover our top product SMC1A Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Kim, Choi, Kim, Woo, Chung: "Reoxygenation following hypoxia activates DNA-damage checkpoint signaling pathways that suppress cell-cycle progression in cultured human lymphocytes." in: FEBS letters, Vol. 581, Issue 16, pp. 3005-12, (2007) (PubMed).

  • 抗原
    SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))
    别名
    SMC1 (SMC1A 产品)
    别名
    CDLS2 antibody, DXS423E antibody, SB1.8 antibody, SMC1 antibody, SMC1L1 antibody, SMC1alpha antibody, SMCB antibody, SMC-1A antibody, NV15570 antibody, 5830426I24Rik antibody, Sb1.8 antibody, Smc1 antibody, Smc1alpha antibody, Smc1l1 antibody, Smcb antibody, mKIAA0178 antibody, smc1 antibody, smc1a antibody, smc1l1 antibody, xSMC1 antibody, smc1aa antibody, structural maintenance of chromosomes 1A antibody, structural maintenance of chromosomes 1A b antibody, structural maintenance of chromosomes 1A L homeolog antibody, SMC1A antibody, smc1a antibody, Smc1a antibody, smc1ab antibody, smc1a.L antibody
    背景

    Description: Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.

    Aliases: SMC1, SMCB, CDLS2, SB1.8, SMC1L1, DXS423E, KIAA0178, MGC138332, SMC1alpha, DKFZp686L19178, SMC1A

    分子量
    143kDa
    基因ID
    8243
    HGNC
    8243
    UniProt
    Q14683
    途径
    Stem Cell Maintenance
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