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RPS6KA3 抗体

RPS6KA3 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4E10 unconjugated
产品编号 ABIN969386
发货至: 中国
  • 抗原 See all RPS6KA3 抗体
    RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
    适用
    • 181
    • 125
    • 65
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 181
    • 16
    • 1
    小鼠
    克隆类型
    • 183
    • 15
    单克隆
    标记
    • 66
    • 13
    • 9
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    • 7
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    • 5
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    This RPS6KA3 antibody is un-conjugated
    应用范围
    • 90
    • 68
    • 67
    • 53
    • 28
    • 24
    • 17
    • 15
    • 12
    • 6
    • 2
    • 2
    • 2
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    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    RSK2 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human RSK2 expressed in E. Coli.
    克隆位点
    4E10
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Dehan, Bassermann, Guardavaccaro, Vasiliver-Shamis, Cohen, Lowes, Dustin, Huang, Taunton, Pagano: "betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis." in: Molecular cell, Vol. 33, Issue 1, pp. 109-16, (2009) (PubMed).

    Cho, Yao, Pugliese, Malakhova, Bode, Dong: "A regulatory mechanism for RSK2 NH(2)-terminal kinase activity." in: Cancer research, Vol. 69, Issue 10, pp. 4398-406, (2009) (PubMed).

  • 抗原
    RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))
    别名
    RSK2 (RPS6KA3 产品)
    别名
    HU-1 antibody, MAPKAPK1A antibody, RSK antibody, RSK1 antibody, CLS antibody, HU-3 antibody, ISPK-1 antibody, MAPKAPK1B antibody, MRX19 antibody, RSK2 antibody, S6K-alpha3 antibody, p90-RSK2 antibody, pp90RSK2 antibody, MPK-9 antibody, Rsk2 antibody, RGD1563860 antibody, id:ibd1103 antibody, rps6ka3 antibody, si:ch211-114c12.12 antibody, wu:fk86e02 antibody, zgc:56006 antibody, zgc:158386 antibody, ribosomal protein S6 kinase A1 antibody, ribosomal protein S6 kinase A3 antibody, ribosomal protein S6 kinase polypeptide 3 antibody, ribosomal protein S6 kinase a, polypeptide 3a antibody, ribosomal protein S6 kinase, polypeptide 3b antibody, RPS6KA1 antibody, RPS6KA3 antibody, Rps6ka3 antibody, rps6ka3a antibody, rps6ka3b antibody
    背景

    Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

    Aliases: RPS6KA3, CLS, RSK, HU-3, RSK2, MRX19, ISPK-1, p90-RSK2, pp90RSK2, MAPKAPK1B, S6K-alpha3

    分子量
    80kDa
    基因ID
    6197
    HGNC
    6197
    UniProt
    P51812
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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