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ROR1 抗体 (AA 30-406)

ROR1 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 2H6 unconjugated
产品编号 ABIN969385
发货至: 中国
  • 抗原 See all ROR1 抗体
    ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
    抗原表位
    • 10
    • 10
    • 9
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-406
    适用
    • 69
    • 32
    • 23
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 71
    • 2
    • 1
    小鼠
    克隆类型
    • 72
    • 2
    单克隆
    标记
    • 28
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ROR1 antibody is un-conjugated
    应用范围
    • 54
    • 26
    • 23
    • 14
    • 5
    • 5
    • 2
    • 2
    • 2
    ELISA, Immunocytochemistry (ICC)
    原理
    ROR1 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Recombinant extracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, expressed in HEK293 cells
    克隆位点
    2H6
    亚型
    IgG1
    Top Product
    Discover our top product ROR1 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Paganoni, Ferreira: "Neurite extension in central neurons: a novel role for the receptor tyrosine kinases Ror1 and Ror2." in: Journal of cell science, Vol. 118, Issue Pt 2, pp. 433-46, (2005) (PubMed).

  • 抗原
    ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
    别名
    ROR1 (ROR1 产品)
    背景

    Description: ROR1, a type I membrane protein, is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases.

    Aliases: ROR1

    分子量
    101kDa
    基因ID
    4919
    HGNC
    4919
    UniProt
    Q01973
    途径
    RTK signaling, WNT signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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