ROR1 抗体 (AA 30-406)
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- 抗原 See all ROR1 抗体
- ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
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抗原表位
- AA 30-406
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ROR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 免疫原
- Recombinant extracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, expressed in HEK293 cells
- 克隆位点
- 2H6
- 亚型
- IgG1
- Top Product
- Discover our top product ROR1 Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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Neurite extension in central neurons: a novel role for the receptor tyrosine kinases Ror1 and Ror2." in: Journal of cell science, Vol. 118, Issue Pt 2, pp. 433-46, (2005) (PubMed).
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Neurite extension in central neurons: a novel role for the receptor tyrosine kinases Ror1 and Ror2." in: Journal of cell science, Vol. 118, Issue Pt 2, pp. 433-46, (2005) (PubMed).
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- 抗原
- ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
- 别名
- ROR1 (ROR1 产品)
- 别名
- NTRKR1 antibody, dJ537F10.1 antibody, 2810404D04Rik antibody, Ntrkr1 antibody, mRor1 antibody, RGD1559469 antibody, ROR1 antibody, fi34e02 antibody, si:dkey-209n16.1 antibody, wu:fi34e02 antibody, receptor tyrosine kinase like orphan receptor 1 antibody, receptor tyrosine kinase-like orphan receptor 1 antibody, ROR1 antibody, Ror1 antibody, ror1 antibody
- 背景
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Description: ROR1, a type I membrane protein, is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases.
Aliases: ROR1
- 分子量
- 101 kDa
- 基因ID
- 4919
- HGNC
- 4919
- 途径
- RTK signaling, WNT signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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