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PTH1R 抗体

PTH1R 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4D2 unconjugated
产品编号 ABIN969372
发货至: 中国
  • 抗原 See all PTH1R 抗体
    PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
    适用
    • 42
    • 17
    • 12
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 35
    • 6
    • 1
    小鼠
    克隆类型
    • 36
    • 6
    单克隆
    标记
    • 31
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTH1R antibody is un-conjugated
    应用范围
    • 28
    • 18
    • 15
    • 10
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    原理
    PTH1R Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human PTH1R expressed in E. Coli.
    克隆位点
    4D2
    亚型
    IgG1
    Top Product
    Discover our top product PTH1R Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Dean, Vilardaga, Potts, Gardella: "Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor." in: Molecular endocrinology (Baltimore, Md.), Vol. 22, Issue 1, pp. 156-66, (2007) (PubMed).

    Yang, Hoang, Kubo, Kawano, Chou, Sowers, Huvos, Meyers, Healey, Gorlick: "Over-expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma." in: International journal of cancer. Journal international du cancer, Vol. 121, Issue 5, pp. 943-54, (2007) (PubMed).

  • 抗原
    PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
    别名
    PTH1R (PTH1R 产品)
    别名
    PFE antibody, PTHR antibody, PTHR1 antibody, PPR antibody, Pthr antibody, Pthr1 antibody, pthr1 antibody, zPTH1R antibody, PTHrel antibody, PTH1 antibody, PTH antibody, parathyroid hormone 1 receptor antibody, parathyroid hormone 1 receptor a antibody, PTH1R antibody, Pth1r antibody, pth1ra antibody
    背景

    Description: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

    Aliases: PFE, PTHR, PTHR1, MGC138426, MGC138452, PTH1R

    分子量
    66kDa
    基因ID
    5745
    HGNC
    5745
    UniProt
    Q03431
    途径
    Regulation of Carbohydrate Metabolic Process
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