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PSIP1 抗体

PSIP1 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 6E4 unconjugated
产品编号 ABIN969370
发货至: 中国
  • 抗原 See all PSIP1 抗体
    PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))
    适用
    • 26
    • 17
    • 11
    • 11
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    宿主
    • 16
    • 13
    小鼠
    克隆类型
    • 16
    • 13
    单克隆
    标记
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSIP1 antibody is un-conjugated
    应用范围
    • 19
    • 9
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    原理
    PSIP1 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human PSIP1 expressed in E. Coli.
    克隆位点
    6E4
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shun, Botbol, Li, Di Nunzio, Daigle, Yan, Lieberman, Lavigne, Engelman: "Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity." in: Journal of virology, Vol. 82, Issue 23, pp. 11555-67, (2008) (PubMed).

  • 抗原
    PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))
    别名
    PSIP1 (PSIP1 产品)
    背景

    Description: Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.

    Aliases: p52, p75, PAIP, DFS70, LEDGF, PSIP2, MGC74712, PSIP1

    分子量
    75kDa
    基因ID
    11168
    HGNC
    11168
    UniProt
    O75475
    途径
    Chromatin Binding, Ribonucleoprotein Complex Subunit Organization
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