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- 抗原 See all PRKDC 抗体
- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PRKDC antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human PRKDC expressed in E. coli.
- 克隆位点
- 3H6
- 亚型
- IgG1
- Top Product
- Discover our top product PRKDC Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36311-20, (2008) (PubMed).
: "EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 35, pp. 12791-6, (2008) (PubMed).
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HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36311-20, (2008) (PubMed).
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- 抗原
- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
- 别名
- PRKDC (PRKDC 产品)
- 别名
- DNA-PKcs antibody, DNAPK antibody, DNPK1 antibody, HYRC antibody, HYRC1 antibody, XRCC7 antibody, p350 antibody, DNA-PKCS antibody, dna-pkcs antibody, dnapk antibody, dnpk1 antibody, hyrc antibody, hyrc1 antibody, prkdc-A antibody, xrcc7 antibody, PRKDC antibody, AI326420 antibody, AU019811 antibody, DNAPDcs antibody, DOXNPH antibody, dxnph antibody, p460 antibody, scid antibody, slip antibody, protein kinase, DNA-activated, catalytic polypeptide antibody, protein kinase, DNA-activated, catalytic polypeptide L homeolog antibody, DNA-dependent protein kinase catalytic subunit antibody, protein kinase, DNA activated, catalytic polypeptide antibody, PRKDC antibody, prkdc.L antibody, LOC100633457 antibody, Prkdc antibody
- 背景
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Description: The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity, PRKDC must be bound to DNA to express its catalytic properties.
Aliases: HYRC, p350, DNAPK, DNPK1, HYRC1, XRCC7, DNA-PKcs, PRKDC
- 分子量
- 46.9 kDa
- 基因ID
- 5591
- HGNC
- 5591
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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