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PRKAA1 抗体

PRKAA1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2B7 unconjugated
产品编号 ABIN969364
发货至: 中国
  • 抗原 See all PRKAA1 抗体
    PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
    适用
    • 157
    • 127
    • 83
    • 25
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    人, 小鼠, 大鼠, 猴
    宿主
    • 157
    • 17
    • 1
    小鼠
    克隆类型
    • 148
    • 27
    单克隆
    标记
    • 82
    • 10
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    This PRKAA1 antibody is un-conjugated
    应用范围
    • 133
    • 54
    • 44
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    • 40
    • 37
    • 33
    • 18
    • 13
    • 9
    • 7
    • 3
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human PRKAA1 expressed in E. coli.
    克隆位点
    2B7
    亚型
    IgG1
    Top Product
    Discover our top product PRKAA1 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Pan, Yang, Cao, Song, Wallin, Kivlin, Lu, Hu, Di, Wan: "AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells." in: Oncology reports, Vol. 20, Issue 6, pp. 1553-9, (2008) (PubMed).

    Egawa, Kamata, Kushiyama, Sakoda, Fujishiro, Horike, Yoneda, Nakatsu, Ying, Jun, Tsuchiya, Takata, Kurihara, Asano: "Long-term forskolin stimulation induces AMPK activation and thereby enhances tight junction formation in human placental trophoblast BeWo cells." in: Placenta, Vol. 29, Issue 12, pp. 1003-8, (2008) (PubMed).

  • 抗原
    PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
    别名
    PRKAA1 (PRKAA1 产品)
    别名
    AMPK antibody, AMPKa1 antibody, cb116 antibody, im:7154392 antibody, sb:cb130 antibody, wu:fa94c10 antibody, AMPK1 antibody, AMPKalpha1 antibody, AI194361 antibody, AI450832 antibody, AL024255 antibody, C130083N04Rik antibody, ampk antibody, ampka1 antibody, PRKAA1 antibody, protein kinase AMP-activated catalytic subunit alpha 1 antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antibody, PRKAA1 antibody, prkaa1 antibody, Prkaa1 antibody, prkaa1.L antibody
    背景

    Description: The protein belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

    Aliases: AMPK, AMPKa1, MGC33776, MGC57364, PRKAA1

    分子量
    64 kDa
    基因ID
    5562
    HGNC
    5562
    途径
    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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