PRKAA1 抗体
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- 抗原 See all PRKAA1 抗体
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
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适用
- 人, 小鼠, 大鼠, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PRKAA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human PRKAA1 expressed in E. coli.
- 克隆位点
- 2B7
- 亚型
- IgG1
- Top Product
- Discover our top product PRKAA1 Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells." in: Oncology reports, Vol. 20, Issue 6, pp. 1553-9, (2008) (PubMed).
: "Long-term forskolin stimulation induces AMPK activation and thereby enhances tight junction formation in human placental trophoblast BeWo cells." in: Placenta, Vol. 29, Issue 12, pp. 1003-8, (2008) (PubMed).
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AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells." in: Oncology reports, Vol. 20, Issue 6, pp. 1553-9, (2008) (PubMed).
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- 抗原
- PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
- 别名
- PRKAA1 (PRKAA1 产品)
- 别名
- AMPK antibody, AMPKa1 antibody, cb116 antibody, im:7154392 antibody, sb:cb130 antibody, wu:fa94c10 antibody, AMPK1 antibody, AMPKalpha1 antibody, AI194361 antibody, AI450832 antibody, AL024255 antibody, C130083N04Rik antibody, ampk antibody, ampka1 antibody, PRKAA1 antibody, protein kinase AMP-activated catalytic subunit alpha 1 antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit antibody, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antibody, PRKAA1 antibody, prkaa1 antibody, Prkaa1 antibody, prkaa1.L antibody
- 背景
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Description: The protein belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Aliases: AMPK, AMPKa1, MGC33776, MGC57364, PRKAA1
- 分子量
- 64 kDa
- 基因ID
- 5562
- HGNC
- 5562
- 途径
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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