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MAPKAP Kinase 5 抗体

MAPKAPK5 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 7H10B4 unconjugated
产品编号 ABIN969362
发货至: 中国
  • 抗原 See all MAPKAP Kinase 5 (MAPKAPK5) 抗体
    MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
    适用
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    宿主
    • 85
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    小鼠
    克隆类型
    • 89
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    单克隆
    标记
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    This MAPKAP Kinase 5 antibody is un-conjugated
    应用范围
    • 74
    • 37
    • 27
    • 27
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of PRAK expressed in E. coli.
    克隆位点
    7H10B4
    亚型
    IgG1
    Top Product
    Discover our top product MAPKAPK5 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Paliga, Natale, Watson: "p38 mitogen-activated protein kinase (MAPK) first regulates filamentous actin at the 8-16-cell stage during preimplantation development." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 97, Issue 8, pp. 629-40, (2005) (PubMed).

    Wijtten, Prak, Lemme, Langhout: "Effect of different dietary ideal protein concentrations on broiler performance." in: British poultry science, Vol. 45, Issue 4, pp. 504-11, (2004) (PubMed).

    New, Jiang, Han: "Regulation of PRAK subcellular location by p38 MAP kinases." in: Molecular biology of the cell, Vol. 14, Issue 6, pp. 2603-16, (2003) (PubMed).

  • 抗原
    MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
    别名
    PRAK (MAPKAPK5 产品)
    别名
    MAPKAPK5 antibody, MK5 antibody, PRAK antibody, MAPKAP-K5 antibody, MK-5 antibody, mitogen-activated protein kinase-activated protein kinase 5 antibody, MAP kinase-activated protein kinase 5 antibody, MAPKAPK5 antibody, mapkapk5 antibody, Mapkapk5 antibody
    背景

    Description: PRAK (p38-regulated /activated kinase), also referred to as mitogen-activated protein kinase (MAPK)-activated protein kinase (MAPKAPK)-5, is an ubiquitously expressed serine/threonine kinase regulated by p38a and p38ß MAP kinases. Activated JNK, p38? or p38d are unable to induce phosphorylation of PRAK in vitro. Phosphorylation of PRAK occurs in vivo in response to p38 activation by stress-related extracellular stimuli including UV light, oxidation and proinflammatory cytokines. Two other substrates for p38, MAPKAPK-2 and MAPKAPK-3/3pK, share approximately 45 % sequence homology with PRAK including the phosphorylation motif recognized by p38, Lys-X-Thr-Pro. Activated PRAK has been shown to specifically phosphorylate HSP 27 in vitro, suggesting that the protein may play a role in stress-induced small heat shock protein phosphorylation in vivo.

    Aliases: PRAK, MAPKAPK5

    基因ID
    8550
    HGNC
    8550
    途径
    MAPK Pathway
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