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- 抗原 See all PPP1CA 抗体
- PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PPP1CA antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- PPP1CA Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human PPP1CA expressed in E. Coli.
- 克隆位点
- 5E9
- 亚型
- IgG1
- Top Product
- Discover our top product PPP1CA Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1." in: The Journal of biological chemistry, Vol. 284, Issue 38, pp. 25576-84, (2009) (PubMed).
: "Direct interaction between myocyte enhancer factor 2 (MEF2) and protein phosphatase 1alpha represses MEF2-dependent gene expression." in: Molecular and cellular biology, Vol. 29, Issue 12, pp. 3355-66, (2009) (PubMed).
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Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1." in: The Journal of biological chemistry, Vol. 284, Issue 38, pp. 25576-84, (2009) (PubMed).
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- 抗原
- PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
- 别名
- PPP1CA (PPP1CA 产品)
- 背景
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Description: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Aliases: PP-1A, PPP1A, PP1alpha
- 分子量
- 38kDa
- 基因ID
- 5499
- HGNC
- 5499
- UniProt
- P62136
- 途径
- M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
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