Prohibitin 抗体
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- 抗原 See all Prohibitin (PHB) 抗体
- Prohibitin (PHB)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Prohibitin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- PHB Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human PHB expressed in E. Coli.
- 克隆位点
- 5H7
- 亚型
- IgG1
- Top Product
- Discover our top product PHB Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Nuclear matrix protein, prohibitin, was down-regulated and translocated from nucleus to cytoplasm during the differentiation of osteosarcoma MG-63 cells induced by ginsenoside Rg1, cinnamic acid, and tanshinone IIA (RCT)." in: Journal of cellular biochemistry, Vol. 108, Issue 4, pp. 926-34, (2009) (PubMed).
: "Prohibitin interacts with phosphatidylinositol 3,4,5-triphosphate (PIP3) and modulates insulin signaling." in: Biochemical and biophysical research communications, Vol. 390, Issue 3, pp. 1023-8, (2009) (PubMed).
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Nuclear matrix protein, prohibitin, was down-regulated and translocated from nucleus to cytoplasm during the differentiation of osteosarcoma MG-63 cells induced by ginsenoside Rg1, cinnamic acid, and tanshinone IIA (RCT)." in: Journal of cellular biochemistry, Vol. 108, Issue 4, pp. 926-34, (2009) (PubMed).
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- 抗原
- Prohibitin (PHB)
- 别名
- PHB (PHB 产品)
- 别名
- phb1 antibody, MGC75944 antibody, PHB antibody, Phb antibody, ACYPI000080 antibody, phb antibody, PHB1 antibody, Bap32 antibody, sr:nyz128 antibody, wu:fa18f07 antibody, wu:fb09f05 antibody, prohibitin1 antibody, xphb1 antibody, prohibitin antibody, prohibitin-2 antibody, prohibitin L homeolog antibody, PHB antibody, phb antibody, LOC484431 antibody, LOC5576054 antibody, Phb antibody, phb.L antibody
- 背景
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Description: Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Aliases: PHB1
- 分子量
- 30kDa
- 基因ID
- 5245
- HGNC
- 5245
- UniProt
- P35232
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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