PGA5 抗体
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- 抗原 See all PGA5 抗体
- PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PGA5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 原理
- PGA5 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human PGA5 expressed in E. Coli.
- 克隆位点
- 2C1
- 亚型
- IgG1
- Top Product
- Discover our top product PGA5 Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))
- 别名
- PGA5 (PGA5 产品)
- 别名
- PGA3 antibody, PGA4 antibody, 1110035E17Rik antibody, Pepf antibody, pepsinogen 5, group I (pepsinogen A) antibody, pepsinogen 5, group I antibody, PGA5 antibody, Pga5 antibody
- 背景
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Description: PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity ( pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.
Aliases: Pepsinogen 5, Pepsin A
- 分子量
- 42kDa
- 基因ID
- 5222
- HGNC
- 5222
- UniProt
- P0DJD9
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