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OLIG2 抗体

OLIG2 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1G11 unconjugated
产品编号 ABIN969331
发货至: 中国
  • 抗原 See all OLIG2 抗体
    OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
    适用
    • 72
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    宿主
    • 79
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    小鼠
    克隆类型
    • 71
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    单克隆
    标记
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    This OLIG2 antibody is un-conjugated
    应用范围
    • 52
    • 38
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    • 6
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    ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    原理
    OLIG2 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human OLIG2 expressed in E. Coli.
    克隆位点
    1G11
    亚型
    IgG1
    Top Product
    Discover our top product OLIG2 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Bonnet-Dupeyron, Combes, Boespflug-Tanguy, Vaurs-Barrière: "Absence of OLIG2 mutations in patients presenting with a severe Pelizaeus-Merzbacher-like leukodystrophy associated with motor neuron dysfunction." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 538-9, (2008) (PubMed).

    Mikami, Hirose, Yoshida, Kawase, Ohnishi, Nagashima, Mukai, Okada, Ikeda: "Predominant expression of OLIG2 over ID2 in oligodendroglial tumors." in: Virchows Archiv : an international journal of pathology, Vol. 450, Issue 5, pp. 575-84, (2007) (PubMed).

  • 抗原
    OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
    别名
    OLIG2 (OLIG2 产品)
    别名
    olig3.2 antibody, MGC89336 antibody, OLIG2 antibody, BHLHB1 antibody, OLIGO2 antibody, PRKCBP2 antibody, RACK17 antibody, bHLHe19 antibody, wu:fc64g09 antibody, AI604895 antibody, Bhlhb1 antibody, Olg-2 antibody, Oligo2 antibody, RK17 antibody, oligodendrocyte transcription factor 4 antibody, oligodendrocyte transcription factor 2 antibody, oligodendrocyte lineage transcription factor 2 antibody, olig4 antibody, OLIG2 antibody, Olig2 antibody, olig2 antibody
    背景

    Description: This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14,21)(q11.2,q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.

    Aliases: BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19, OLIG2

    分子量
    32kDa
    基因ID
    10215
    HGNC
    10215
    UniProt
    Q13516
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