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- 抗原 See all OLIG2 抗体
- OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This OLIG2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 原理
- OLIG2 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human OLIG2 expressed in E. Coli.
- 克隆位点
- 1G11
- 亚型
- IgG1
- Top Product
- Discover our top product OLIG2 Primary Antibody
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Absence of OLIG2 mutations in patients presenting with a severe Pelizaeus-Merzbacher-like leukodystrophy associated with motor neuron dysfunction." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 538-9, (2008) (PubMed).
: "Predominant expression of OLIG2 over ID2 in oligodendroglial tumors." in: Virchows Archiv : an international journal of pathology, Vol. 450, Issue 5, pp. 575-84, (2007) (PubMed).
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Absence of OLIG2 mutations in patients presenting with a severe Pelizaeus-Merzbacher-like leukodystrophy associated with motor neuron dysfunction." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 538-9, (2008) (PubMed).
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- 抗原
- OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
- 别名
- OLIG2 (OLIG2 产品)
- 别名
- olig3.2 antibody, MGC89336 antibody, OLIG2 antibody, BHLHB1 antibody, OLIGO2 antibody, PRKCBP2 antibody, RACK17 antibody, bHLHe19 antibody, wu:fc64g09 antibody, AI604895 antibody, Bhlhb1 antibody, Olg-2 antibody, Oligo2 antibody, RK17 antibody, oligodendrocyte transcription factor 4 antibody, oligodendrocyte transcription factor 2 antibody, oligodendrocyte lineage transcription factor 2 antibody, olig4 antibody, OLIG2 antibody, Olig2 antibody, olig2 antibody
- 背景
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Description: This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14,21)(q11.2,q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
Aliases: BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19, OLIG2
- 分子量
- 32kDa
- 基因ID
- 10215
- HGNC
- 10215
- UniProt
- Q13516
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