OCT4 抗体
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- 抗原 See all OCT4 (POU5F1) 抗体
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This OCT4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- 4-Oct Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Synthesized peptide derived from internal of human Oct4.
- 克隆位点
- 7E7
- 亚型
- IgG1
- Top Product
- Discover our top product POU5F1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Concise review: isoforms of OCT4 contribute to the confusing diversity in stem cell biology." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 5, pp. 885-93, (2010) (PubMed).
: "[The dual role of OCT4]." in: Médecine sciences : M/S, Vol. 26, Issue 4, pp. 411-6, (2010) (PubMed).
: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, (2010) (PubMed).
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Concise review: isoforms of OCT4 contribute to the confusing diversity in stem cell biology." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 5, pp. 885-93, (2010) (PubMed).
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- 抗原
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- 别名
- 4-Oct (POU5F1 产品)
- 别名
- OCT3 antibody, OCT4 antibody, OTF-3 antibody, OTF3 antibody, OTF4 antibody, Oct-3 antibody, Oct-4 antibody, POU5F1 antibody, gp9 antibody, gp-9 antibody, oct4 antibody, pou2 antibody, POU-2 antibody, cb197 antibody, spg/pou2 antibody, chunp6868 antibody, wu:fd18d06 antibody, NF-A3 antibody, Oct-3/4 antibody, Oct3 antibody, Oct3/4 antibody, Oct4 antibody, Otf-3 antibody, Otf-4 antibody, Otf3 antibody, Otf3-rs7 antibody, Otf3g antibody, Otf4 antibody, POU class 5 homeobox 1 antibody, POU domain, class 5, transcription factor 3 antibody, POU domain, class 5, transcription factor 1 antibody, POU5F1 antibody, pou5f3 antibody, Pou5f1 antibody
- 背景
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Description: This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
Aliases: OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4, MGC22487, POU5F1
- 分子量
- 45kDa
- 基因ID
- 5460
- HGNC
- 5460
- UniProt
- Q01860
- 途径
- Stem Cell Maintenance
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