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OCT4 抗体 (AA 193-360)

POU5F1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D10H6 unconjugated
产品编号 ABIN969327
发货至: 中国
  • 抗原 See all OCT4 (POU5F1) 抗体
    OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
    抗原表位
    • 16
    • 10
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 193-360
    适用
    • 107
    • 58
    • 29
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 97
    • 23
    • 1
    • 1
    小鼠
    克隆类型
    • 89
    • 32
    单克隆
    标记
    • 88
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OCT4 antibody is un-conjugated
    应用范围
    • 99
    • 53
    • 24
    • 20
    • 16
    • 15
    • 15
    • 14
    • 12
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of Oct4 (aa193-360) expressed in E. coli.
    克隆位点
    1D10H6
    亚型
    IgG1
    Top Product
    Discover our top product POU5F1 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Kerkis, Kerkis, Dozortsev, Stukart-Parsons, Gomes Massironi, Pereira, Caplan, Cerruti: "Isolation and characterization of a population of immature dental pulp stem cells expressing OCT-4 and other embryonic stem cell markers." in: Cells, tissues, organs, Vol. 184, Issue 3-4, pp. 105-16, (2007) (PubMed).

    Atlasi, Mowla, Ziaee, Bahrami: "OCT-4, an embryonic stem cell marker, is highly expressed in bladder cancer." in: International journal of cancer. Journal international du cancer, Vol. 120, Issue 7, pp. 1598-602, (2007) (PubMed).

  • 抗原
    OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
    别名
    Oct4 (POU5F1 产品)
    别名
    OCT3 antibody, OCT4 antibody, OTF-3 antibody, OTF3 antibody, OTF4 antibody, Oct-3 antibody, Oct-4 antibody, POU5F1 antibody, gp9 antibody, gp-9 antibody, oct4 antibody, pou2 antibody, POU-2 antibody, cb197 antibody, spg/pou2 antibody, chunp6868 antibody, wu:fd18d06 antibody, NF-A3 antibody, Oct-3/4 antibody, Oct3 antibody, Oct3/4 antibody, Oct4 antibody, Otf-3 antibody, Otf-4 antibody, Otf3 antibody, Otf3-rs7 antibody, Otf3g antibody, Otf4 antibody, POU class 5 homeobox 1 antibody, POU domain, class 5, transcription factor 3 antibody, POU domain, class 5, transcription factor 1 antibody, POU5F1 antibody, pou5f3 antibody, Pou5f1 antibody
    背景

    Description: Oct4: octamer-binding transcription factor-4 (Oct-4, Otf-4) and Oct-3/4, also known as POU5F1(POU class 5 homeobox 1), octamerbinding transcription factor-3 (Oct-3, Otf-3), modulates embryonic stem (ES) cell populations by influencing lineage commitment. Entrez Protein NP_002692. Oct-3/4 sustains stem-cell selfrenewal and differentiation pathways. Transcription factors containing the POU homeodomain regulate tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development. Oct-3/4 is capable of inducing rapid proliferation and tumorigenic properties of ES cells through activation of the UTF1 gene. In humans, two Oct-3/4 isoforms contribute to influencing the undifferentiated phenotype of ES cells. Oct-3/4 pseudogenes localizing to human chromosomes 10 and 8 are reported to be transcribed in certain cancer cell lines and tissues.

    Aliases: OCT3, OTF3, OTF4, MGC22487, POU5F1

    分子量
    38.5 kDa
    基因ID
    5460
    HGNC
    5460
    途径
    Stem Cell Maintenance
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