OCT4 抗体 (AA 193-360)
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- 抗原 See all OCT4 (POU5F1) 抗体
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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抗原表位
- AA 193-360
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This OCT4 antibody is un-conjugated
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应用范围
- ELISA
- 原理
- 5-Oct Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of Oct4 (aa193-360) expressed in E. Coli.
- 克隆位点
- 1D10H6
- 亚型
- IgG1
- Top Product
- Discover our top product POU5F1 Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Isolation and characterization of a population of immature dental pulp stem cells expressing OCT-4 and other embryonic stem cell markers." in: Cells, tissues, organs, Vol. 184, Issue 3-4, pp. 105-16, (2007) (PubMed).
: "OCT-4, an embryonic stem cell marker, is highly expressed in bladder cancer." in: International journal of cancer. Journal international du cancer, Vol. 120, Issue 7, pp. 1598-602, (2007) (PubMed).
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Isolation and characterization of a population of immature dental pulp stem cells expressing OCT-4 and other embryonic stem cell markers." in: Cells, tissues, organs, Vol. 184, Issue 3-4, pp. 105-16, (2007) (PubMed).
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- 抗原
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
- 别名
- Oct4 (POU5F1 产品)
- 背景
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Description: Oct4: octamer-binding transcription factor-4 (Oct-4, Otf-4) and Oct-3/4, also known as POU5F1(POU class 5 homeobox 1), octamerbinding transcription factor-3 (Oct-3, Otf-3), modulates embryonic stem (ES) cell populations by influencing lineage commitment. Entrez Protein NP_002692. Oct-3/4 sustains stem-cell selfrenewal and differentiation pathways. Transcription factors containing the POU homeodomain regulate tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development. Oct-3/4 is capable of inducing rapid proliferation and tumorigenic properties of ES cells through activation of the UTF1 gene. In humans, two Oct-3/4 isoforms contribute to influencing the undifferentiated phenotype of ES cells. Oct-3/4 pseudogenes localizing to human chromosomes 10 and 8 are reported to be transcribed in certain cancer cell lines and tissues.
Aliases: OCT3, OTF3, OTF4, MGC22487, POU5F1
- 分子量
- 38.5kDa
- 基因ID
- 5460
- HGNC
- 5460
- UniProt
- Q01860
- 途径
- Stem Cell Maintenance
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